Accepted Manuscript Synthesis, SAR elucidations and molecular docking study of newly designed Isatin based oxadiazole analogs as potent inhibitors of thymidine phosphorylase Muhammad Tariq Javid, Fazal Rahim, Muhammad Taha, Mohsan Nawaz, Abdul Wadood, Muhammad Ali, Ashik Mosaddik, Syed Adnan Ali Shah, Rai Khalid Farooq PII: S0045-2068(18)30156-1 DOI: https://doi.org/10.1016/j.bioorg.2018.05.011 Reference: YBIOO 2364 To appear in: Bioorganic Chemistry Received Date: 18 February 2018 Revised Date: 6 May 2018 Accepted Date: 14 May 2018 Please cite this article as: M. Tariq Javid, F. Rahim, M. Taha, M. Nawaz, A. Wadood, M. Ali, A. Mosaddik, S. Adnan Ali Shah, R. Khalid Farooq, Synthesis, SAR elucidations and molecular docking study of newly designed Isatin based oxadiazole analogs as potent inhibitors of thymidine phosphorylase, Bioorganic Chemistry (2018), doi: https://doi.org/10.1016/j.bioorg.2018.05.011 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.