09 — Prevention/Epidemiology/Nutrition 123 454 Stress at work burden as new risk factor in patients with acute cerebro- or cardiovascular events: Preliminary findings from INEV@L, a prospective pilot study M. Zeller 1,∗ , E. Salès-Wuillemin 2 , J. Chappé 2 , S. Guinchard 3 , H. Ayari 3 , M. Maza 3 , C. Aboa-Eboulé 4 , D. Truchot 5 , L. Lorgis 3 , M. Giroud 4 , Y. Cottin 3 , Y. Bejot 4 1 Université Bourgogne Franche-Comté, Équipe PEC2, EA 7460 2 Université Bourgogne Franche-Comté, laboratoire PSY-DREPI, EA 7458 3 CHU Dijon Bourgogne, service de cardiologie 4 CHU Dijon Bourgogne, service de neurologie, Dijon 5 Université Bourgogne Franche-Comté, département de psychologie, Besanc ¸on, France ∗ Corresponding author. E-mail address: marianne.zeller@u-bourgogne.fr (M. Zeller) Introduction and aim Although psychosocial factors (PSF) includ- ing work-related stress and low quality of life at work are emerging cardiovascular risk factors, PSF burden remains poorly investigated after acute cerebro- or cardiovascular event (CVE). Methods INEV@L, an ongoing prospective multidisciplinary study, included 156 patients aged < 65 y, currently working and hospitalized for stroke or MI between 1st January 2016 and 31st august 2017. PSF were examined perceived CV disease severity, anxiety/depression, perceived stress at work (PSW), quality of life at work (QLW) through validated questionnaires and semi-conducted interviews. Patients with higher (supramedian) perceived stress at work (PSW) were compared to lower (inframedian) PSW. Results Among the 156 patients included, 121(78%) had acute MI and 35(22%) stroke. Median (IQR) age was 53(48—58) years, and 18% were women, 56% smokers and had high PSW [15(10—20)], but a low QLW [85(75—95)]. Patients with a higher score to PSW, had similar risk factors including age (P = 0.450), women (0.542), hyper- tension (P = 0.791), smoking (P = 0.384), diabetes (P = 0.193), obesity (P = 0.995) than patients with a lower score. Although high PSW patients showed a trend toward lower education level (P = 0.067), marital status, and socio-economic categories were similar for both groups. Elevated perceived disease severity was more common (49 vs. 19%) in stressed patients. Patients with high PSW are more anxious (78 vs. 25%, P < 0.001), and had twice more depressive symp- toms (19 vs. 9%, P =0.100). QLW was significantly lower in high PSW patients (81 ± 16 vs. 90 ± 13, P < 0.001). Moreover, QLW was strongly correlated with PSW (r = -0.433, P < 0.001). Conclusion These preliminary data from a prospective pilot study shows a high PSF burden in patients hospitalized for acute CVE. If confirmed at a larger scale, our data could identify new opportuni- ties for secondary preventive strategies. Disclosure of interest The authors declare that they have no com- peting interest. https://doi.org/10.1016/j.acvdsp.2018.10.271 245 Cluster analysis of the 2822 patients with heart failure included in the Multicenter French Survey OFICSEL L. Bonnefous 1,∗ , M. Bezard 2 , D. Bodez 2 , E. Berthelot 3 , T. Pezel 4 , J. Gauthier 5 , F. Beauvais 6 , J. Mansourati 7 , F. Koukoui 8 , F. Roubille 9 , A. Barigou 10 , J.N. Trochu 11 , A. Le Helloco 12 , P. Gibelin 13 , C. Chong-Nguyen 14 , F. Bauer 15 , U. Vergeylen 16 , B. Gellen 17 , E. Audureau 1 , T. Damy 2 1 Public Health 2 Cardiology, AP—HP, hôpital Henri Mondor, Créteil 3 Cardiology, AP—HP, hôpital du Kremlin-Bicêtre, Kremlin-Bicêtre 4 Cardiology, AP—HP, hôpital Bichat, Claude-Bernard, Paris 5 Cardiologist, Nîmes 6 Cardiology, AP—HP, hôpital Lariboisière, Paris 7 Cardiology, hôpital La Cavale Blanche, Brest 8 Cardiac Rehabilitation, CHSF, centre hospitalier Sud Francilien, Corbeil Essonnes 9 Cardiology, CHU Montpellier, Montpellier 10 Cardiac rehabilitation, AP—HP, Hôpital Albert Chenevier, Créteil 11 Cardiology, CHU Nantes, Nantes 12 Cardiology, CHU Rennes, Rennes 13 Cardiology, CHU Nice, Nice 14 Cardiology, hôpital Simone Veil, Eaubonne 15 Cardiology, CHU Rouen, Rouen 16 Cardiology, CHU Montfermeil, Montfermeil 17 Cardiologist, Poitiers, France ∗ Corresponding author. E-mail address: bonnefous.louis.x@gmail.com (L. Bonnefous) Background Heart Failure (HF) is a major public health problem resulting in high rates of hospitalization and mortality. So far, most HF Surveys have included a selected population of patients with HF and involved mainly one type of cardiologic practice. There is a need for more information on the whole HF population. Purpose To collect data on a large French HF popula- tion (de novo/chronic/acute; out and in-patients; consulta- tion/hospitalization/rehabilitation; all LVEF classes and any type of cardiologic practice) and to assess low sodium diet prescription and adherence. Methods Prospective enrolment during 6 months in 2017. Data collection included biological, clinical, demographic, dietetary, echocardiographic and treatment characteristics. Results Supervised and unsupervised analysis methods from the data mining and machine learning fields can be performed to exploit data. Baseline variables involved for the analysis (NYHA classes, NTproBNP, Creatinin, BMI, ...) are studied among descriptive varia- bles (Age, Sex, Weight, ...). Cluster analysis performed are based on Hierarchical Ascending Approaches in Euclidean distance and on the production of Self- Organizing Maps (SOMs) with the statistical software R. Complete data analysis with identification of new patient profiles will be shown at the congress. Conclusion Combining a large representative and non selective French HF population, cluster analysis will allow to identify spe- cific patient profiles constituting homogeneous groups within the sampled population reflecting the severity of their heart condition. New data will be shown during the congress. Disclosure of interest The authors declare that they have no com- peting interest. https://doi.org/10.1016/j.acvdsp.2018.10.272 335 Clinical and coronary angiography characteristics of acute myocardial infarction occurring during sport activities: 2011—2017 data from the ‘‘obseRvatoire des Infarctus de Côte d’Or’’ (RICO) survey F. Chagué 1 , G. Porot 1 , A. Gudjoncik 1 , R. Robert 1 , J.C. Beer 1 , G. Molins 2 , M. Maza 1 , Y. Cottin 1 , M. Zeller 3,∗ 1 CHU Dijon-Bourgogne 2 Hôpital privé Dijon-Bourgogne, service de cardiologie 3 Université Bourgogne Franche-Comté, Équipe PEC2, EA 7460, Dijon, France ∗ Corresponding author. E-mail address: marianne.zeller@u-bourgogne.fr (M. Zeller)