Please cite this article in press as: Farzanegi P, et al. Effects of upper- and lower-extremity resistance training on serum vascular endothelial growth factor, myostatin, endostatin and follistatin levels in sedentary male students. Sci sports (2020), https://doi.org/10.1016/j.scispo.2020.02.013 ARTICLE IN PRESS +Model SCISPO-3441; No. of Pages 6 Science & Sports (2020) xxx, xxx.e1—xxx.e6 Disponible en ligne sur ScienceDirect www.sciencedirect.com ORIGINAL ARTICLE Effects of upper- and lower-extremity resistance training on serum vascular endothelial growth factor, myostatin, endostatin and follistatin levels in sedentary male students Effets comparés d’un entraînement en résistance des membres supérieurs et des membres inférieurs sur le VEGF, la myostatine, l’endostatine et la follistatine chez des étudiants masculins sédentaires P. Farzanegi a,* , M. Zamani b , A. Khalili a , H. Dehghani a , R. Fotohi a , M.R. Ghanbarpour a , S.A. Hosseini c , M. Peeri b , S.R.-A. Abad d , M.A. Azarbayjani b a Department of Exercise Physiology, Sari Branch, Islamic Azad University, Sari, Iran b Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran c Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran d Department of Physical Education, Pardis Branch, Islamic Azad University, Pardis, Iran Received 3 July 2018; accepted 21 February 2020 KEYWORDS Sedentary students; Resistance trainings; VEGF; Myostatin; Endostatin; Follistatin Summary This study aims to evaluate the effect of upper- and lower-extremity resistance programs on serum levels of vascular endothelial growth factor, myostatin, endostatin and follistatin in sedentary male students. Our data have revealed that upper- and lower-extremity resistance trainings result in favorable alterations in serum levels of ES, VEGF, FS and MSTN In sedentary students. © 2020 Published by Elsevier Masson SAS. ∗ Corresponding author. E-mail address: parvin.farzanegi@gmail.com (P. Farzanegi). https://doi.org/10.1016/j.scispo.2020.02.013 0765-1597/© 2020 Published by Elsevier Masson SAS.