DOI: https://doi.org/10.53350/pjmhs221610511 ORIGINAL ARTICLE P J M H S Vol. 16, No. 10, October, 2022 511 Studies on the Comparative Effect of Organic and Synthetic Feed on the Growth and Serum Metabolites of Broiler Chicks SADIA SHAHID 1 , MUHAMMAD TAHIR 1 , AMARA AKHTAR 1 , MUHAMMAD USMAN 1 , SAJID ABBAS KHAN 2 , HAFEEZ ULLAH 3 , LARAIB MARYUM 3 , SAJID RAZA KHAN 4 , QAMAR SHAHZAD AHMED 1 1 Department of Zoology Wildlife and Fisheries, University of Agriculture, Faisalabad, Pakistan. 2 Department of Zoology, Government college university Faisalabad, Pakistan. 3 Department of Zoology , The University of Lahore, Pakistan. 4 Department of Zoology, Govt. Post graduate college kot sultan, Pakistan. Corresponding author: Amara Akhtar, Email: amara.akhtar47@gmail.com ABSTRACT Introduction: Modern broiler production efficiency is built on the improved feed for high growth and egg output. Growth performance of broilers greatly influenced by the feed contents. Objective: The objective of this study was to analyze the impact of organic and synthetic feed on the growth, feed utilization and serum metabolites of broilers chicken. Material and Methods: This experiment was conducted for 28 days on broiler chickens. Broilers were divided into five treatments such as T0, T1, T2, T3 and T4. Control group T0 received basal diet. T1 and T2 received organic feed. T3 and T4 received synthetic feed. Results: All the feed were given at the levels of 3% and 6%. Feed were given orally in the form of pellets. Practical implication: Growth performance were observed and recorded at weekly basis. After the completion of trial, blood sample were taken for the analysis of serum metabolites. Conclusion: Results showed that value of WG, absolute weight gain and SGR were increased significantly (p<0.05) in combine treatment T2 (6% organic feed) with respect to T0 (control group). Feed intake and FCR was significantly (p<0.05) in treatment T2. Serum metabolites i.e. cholesterol, triglycerides, glucose and total protein were significantly analyzed (p<0.05).The result of present study explained that T2 having organic feed showed better growth performance of broiler chickens. Keywords: broilers chicken, feed requirement, weight gain, FCR, serum metabolites, INTRODUCTION Poultry industry is globalized and expanding due to rising demand of food. Broiler sector is the fastest expanding and most adaptable sector of livestock industries 1 . Good quality in feed formulation and better growth performance improve efficiency of the broilers farming. Broilers generally achieve the highest growth rates and minimum cost per unit of production owing to strong feed conversion which gives them an edge over other livestock species especially ruminants which cannot do so to the same level 2 . Food processing sector estimates a worldwide production of 130 million tons of chicken meat in 2020 and become the world's most widely consumed animal meat 3 . Aspects including increasing human population, rising income, urbanization and the health- benefit relationship all contribute to the product's high demand, which in turn leads to higher production 4 . Broiler industry in developing countries is troubled by feed ingredients shortage. Feed cost comprises 70 percent of the overall cost of broiler production and the requirement of low cost feed is the main issue for industry. Specialists in livestock are pursuing natural feed materials that are healthy for both people and the environment 5. . Feeding is most important input in chicken’s production. High-quality feed is critical for broilers growth. Nutritional values of the diet in broilers depend upon its high palatability and accessibility of ingredients. Feed form is considered to have a very significant impact on broiler growth 6 . Pellet form of feeding improved growth performance by increased digestibility and high protein bioavailability . Feed containing strong balance of feed conversion ratio resulted in maximum growth development. The more effective and promising approaches of feeding in broilers are organic and synthetic feed 7 . Organic feed is produced without utilization of any foreign substances such as synthetic, pesticides, antibiotics or hormones 8 . Organic feed is natural and untreated provides healthier flock and more nutrition. It delivers a richer and better taste 9 . Food substances or products that are manufactured artificially rather than through natural processes are referred to as synthetic feed. Synthetic substances supply essential amino acids like methionine and lysine. These amino acids enhance the protein synthesis and feed efficiency of broilers .The organic food sector has grown at a rapid rate of up to 20% each year. Due to the rising demand for meat and egg products, broilers fed organic feed are increasingly accessible to the typical consumer 10 . Organic feed requires intensive human labor. There are following ingredients are needed to mix organic diet on farm like wheat corn and soybean 11 . Wheat is one of the best organic feed ingredients. It is commonly available and good source of energy. Corn is the easiest grain for chickens to digest and is low in fiber. It provides 7.5% crude protein 12 . For broilers, soybean is a rich source of fat and protein. Soybean seed contains a trypsin inhibitor that can severely interfere with digestion in a broilers gut and used must be heat treated to inactivate this compound 13 Synthetic feed added to the basic feed, usually in small amounts, to raise the feed's quality. Along with increasing the feed ingredients' digestibility, it enhances the health and performance of broilers. There are following ingredients are used in the formation of synthetic feed like fishmeal and poultry by products meal 14 . Fishmeal is an excellent source of protein in broilers. Unsaturated fatty acids, essential minerals and vitamins are well-balanced in fishmeal. Broilers diet with the inclusion of poultry byproduct meal provides high protein content. Although broiler nutrition is used up to 7.5% of poultry byproduct meal, efficiency and egg production are still not negatively affected 15 . Growth performance traits like increased body weight and growth rate have been produced due to strong selection pressure. It enabling broilers to have a greater hunger and as a result consume more voluntary feed per day 16 . Blood parameters are crucial for determining the feed utilization and growth in broilers are serum metabolites. Serum metabolites which are serum glucose and cholesterol used as a feed intake predictors 17 Broilers with improved feed conversion have higher digestive efficiency and they will achieve high growth rate 18 .Therefore, The purpose of the experiment was to examine the effects of organic and synthetic feed on broiler chicken growth, feed utilization and serum metabolites. Objectives: The main objectives of the present study were:  To examine the influence of serum metabolites in broilers chicken when given to organic and synthetic feed.  To determine the impact of organic and synthetic feed on the growth and feed utilization of broilers.