Hindawi Publishing Corporation ISRN Ophthalmology Volume 2013, Article ID 264604, 8 pages http://dx.doi.org/10.1155/2013/264604 Research Article Profile of Gaze Dysfunction following Cerebrovascular Accident Fiona J. Rowe, 1 David Wright, 2 Darren Brand, 3 Carole Jackson, 4 Shirley Harrison, 5 Tallat Maan, 6 Claire Scott, 7 Linda Vogwell, 8 Sarah Peel, 9 Nicola Akerman, 10 Caroline Dodridge, 11 Claire Howard, 12 Tracey Shipman, 13 Una Sperring, 14 Sonia MacDiarmid, 15 and Cicely Freeman 16 1 Department of Health Services Research, Tompson Yates Building, University of Liverpool, Brownlow Hill, Liverpool L69 3GB, UK 2 Altnagelvin Hospitals HHS Trust, Altnagelvin BT47 6SB, UK 3 NHS Ayrshire and Arran, Ayr KA6 6DX, UK 4 Royal United Hospitals Bath NHS Trust, Bath BA1 3NG, UK 5 Bury Primary Care Trust, Bury BL9 7TD, UK 6 Durham and Darlington Hospitals NHS Foundation Trust, Durham DH1 5TW, UK 7 Ipswich Hospital NHS Trust, Ipswich IP4 5PD, UK 8 Gloucestershire Hospitals NHS Foundation Trust, Gloucester GL1 3NN, UK 9 St Helier General Hospital, Jersey JE2 3QS, UK 10 University Hospital NHS Trust, Nottingham NG7 2UH, UK 11 Oxford Radclife Hospitals NHS Trust, Oxford OX3 9DU, UK 12 Salford Primary Care Trust, Salford M6 8HD, UK 13 Shefeld Teaching Hospitals NHS Foundation Trust, Shefeld S10 2TB, UK 14 Swindon and Marlborough NHS Trust, Swindon SN3 6BB, UK 15 Wrightington, Wigan and Leigh NHS Trust, Wigan WN1 2NN, UK 16 Worcestershire Acute Hospitals NHS Trust, Worcester WR5 1DD, UK Correspondence should be addressed to Fiona J. Rowe; rowef@liverpool.ac.uk Received 8 July 2013; Accepted 21 August 2013 Academic Editors: A. Daxer, R. Saxena, and I. J. Wang Copyright © 2013 Fiona J. Rowe et al. Tis is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Aim. To evaluate the profle of ocular gaze abnormalities occurring following stroke. Methods. Prospective multicentre cohort trial. Standardised referral and investigation protocol including assessment of visual acuity, ocular alignment and motility, visual feld, and visual perception. Results. 915 patients recruited: mean age 69.18 years (SD 14.19). 498 patients (54%) were diagnosed with ocular motility abnormalities. 207 patients had gaze abnormalities including impaired gaze holding (46), complete gaze palsy (23), horizontal gaze palsy (16), vertical gaze palsy (17), Parinaud’s syndrome (8), INO (20), one and half syndrome (3), saccadic palsy (28), and smooth pursuit palsy (46). Tese were isolated impairments in 50% of cases and in association with other ocular abnormalities in 50% including impaired convergence, nystagmus, and lid or pupil abnormalities. Areas of brain stroke were frequently the cerebellum, brainstem, and diencephalic areas. Strokes causing gaze dysfunction also involved cortical areas including occipital, parietal, and temporal lobes. Symptoms of diplopia and blurred vision were present in 35%. 37 patients were discharged, 29 referred, and 141 ofered review appointments. 107 reviewed patients showed full recovery (4%), partial improvement (66%), and static gaze dysfunction (30%). Conclusions. Gaze dysfunction is common following stroke. Approximately one-third of patients complain of visual symptoms, two thirds show some improvement in ocular motility. 1. Introduction Ocular motility (eye movement) problems are reported com- monly following stroke in up to 68% of cases [1–5]. Tese problems can include cranial nerve palsy [6], vergence and accommodative dysfunction [3], strabismus [2, 7], and nystagmus [8]. Such eye movement abnormalities can cause symptoms of diplopia, blurred vision, compensatory head