Review Artcle Chetnad Health City Medical Journal (P-ISSN: 2277-8845 & E-ISSN: 2278-2044) Copyright (c) 2022: Author(s). Published by Advanced Research Publicatons Chettinad Health City Medical Journal Volume 11, Issue 2 - 2022, Pg. No. 62-68 Peer Reviewed & Open Access Journal Corresponding Author: Vyoma Agarwal, Department of Home Science, IIS (Deemed to be University), Jaipur, Rajasthan, India. E-mail Id: vyoma.agarwal@iisuniv.ac.in Orcid Id: htps://orcid.org/0000-0002-6816-6803 How to cite this artcle: Agarwal V, Singh S, Gupta R. Correlaton of Neurodegeneratve Diseases with Oxidatve Stress and Nutriton. Chetnad Health City Med J. 2022;11(2):62-68. Date of Submission: 2022-05-10 Date of Acceptance: 2022-06-23 I N F O A B S T R A C T Technology or ease of doing work might be the greatest boon to this era, but it is stll a bane for our health and life. Sitng in front of laptops or computers for several hours (sedentary lifestyle), using cell phones, watching television, skipping meals or eatng junk/ fast food, lack of physical actvites, stress, etc. increase the risk of many lifestyle diseases. All the above-mentoned habits increase the count of free radicals in our body and due to a lack of endogenous and exogenous antoxidants, the body cannot combat oxidatve stress. Thus, the chances of occurrence of several chronic diseases like cancer, atherosclerosis, cardiovascular diseases, neurodegeneratve diseases, rheumatoid arthrits, chronic infammatons, etc. increase. There are several factors contributng to neurodegeneraton of the brain and neurons, in which oxidatve stress plays an important role. This review artcle is the compilaton of research done by several other researchers on Neurodegeneratve Diseases (NDDs) and is primarily focused on beter understanding a few basic questons like the correlaton of oxidatve stress and nutriton to neurodegeneraton, NDDs, their diferent types, symptoms and causes followed by establishing a relaton between oxidatve stress and nutriton with the help of several studies carried out by researchers in this context. Keywords: Antoxidants, Atherosclerosis, Cardiovascular Disease, Chronic, Interventon, Oxidatve Stress, Sedentary Correlation of Neurodegenerative Diseases with Oxidative Stress and Nutrition Vyoma Agarwal 1 , Simran Singh 2 , Ruchika Gupta 2 1 PhD (Foods and Nutriton), 2 MSc Foods and Nutriton, Department of Home Science, IIS (Deemed to be University), Jaipur, Rajasthan, India. DOI: htps://doi.org/10.24321/2278.2044.202217 Introduction ‘Neurodegeneraton’ is a term formed by the combinaton of two words - ‘neuro’, signifying nerve cell and ‘degeneraton’, signifying progressive damage. 1 Neurodegeneratve diseases (NDDs) lead to the loss of nerve cells, causing either sensory dysfuncton (dementa) or functonal loss (ataxia). 2 NDDs cause progressive damage in neural cells and neuronal loss, thereby compromising motor or cognitve functons. 3 The causes of many NDDs are stll a mystery and even though researchers found about a few of them, their mechanisms of acton are stll not properly known. Some of these causes are increased levels of free radicals and decreased levels of endogenous antoxidants i.e. oxidatve stress (OS), protein misfolding, protein degradaton, membrane damage, mitochondrial dysfunctoning, excitotoxicity, high levels of lipids in the brain, DNA damage, genetc mutatons, apoptosis, inflammation, etc. 4 General symptoms of neurodegeneraton are memory loss, frequent headaches, impairment in daily physical and functonal actvites of life, cognitve decline, difculty in balance, speech loss,