IAJPS 2019, 07 [07], 14150-14154 Shumaila Israr et al ISSN 2349-7750 www.iajps.com Page 14150 CODEN [USA]: IAJPBB ISSN: 2349-7750 INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES Available online at: http://www.iajps.com Research Article FREQUENCY OF LOW SERUM FERRITIN LEVEL IN PATIENTS OF DECOMPENSATED CHRONIC LIVER DISEASE SECONDARY TO HEPATITIS C VIRUS INFECTION Dr. Shumaila Israr 1 , Dr. Qurat ul Ain 2 , Dr. Asma Ambreen 3 , Dr. Tahir Iqbal 4 , Dr. Sobia Jamil 5 , Dr. Atif Abbas 6 1 MBBS FCPS Medicine Fauji Foundation Hospital Rawalpindi, Cell No. 0334 5276731 E-mail: shumaila.israr216@yahoo.com. 2 MBBS FCPS Med Senior Registrar Fauji Foundation Hospital Rawalpindi Cell No: 03338268884, E-mail: qnaib@yahoo.com. 3 MBBS, MCPS Med, FCPS med, FCPS Pulmonology, Assistant Professor Medicine at Fauji Foundation Hospital Rawalpindi Cell No: 03325726510, E-mail: asmayasir2005@hotmail.com 4 Medical Specialist, Oman Health Authority. Cell No: 03455160153, E-mail: Tahir.iqbal801@gmail.com. 5 Postgraduate Trainee Medicine at Fauji Foundation Hospital Rawalpindi Cell No: 03009877889, E-mail: sobiajamilkhan@gmail.com. 6 MBBS FCPS med, Senior registrar at Fauji Foundation Hospital Rawalpindi Cell No: 03315183973, E-mail: atif_abbas20@yahoo.com. Article Received: May 2019 Accepted: June 2019 Published: July 2019 Abstract: Objectives: To determine the frequency of low serum ferritin level in patients of decompensated chronic liver disease secondary to hepatitis C virus infection. Place of study: This descriptive cross-sectional study was conducted in Department of General medicine, Fauji Foundation Hospital Rawalpindi during 1 st Jan,2017 to 1 st Jun 2017. Study design: The sampling technique we used for this purpose was non-probability consecutive sampling. After taking all aseptic measures blood was taken and stored in a serum bottle. The bottle was clearly marked with the name and hospital number of the patients. The serum bottle was sent to the hospital laboratory in order to check serum iron, ferritin, TIBC, and LFT, s. The sample was sent to the hematology department in order to check for the serum iron and ferritin reports were verified by consultant. The results were recorded on proforma accordingly. Results: Data was entered and analyzed in SPSS version 16.0. Total 165 patients were included according to the inclusion criteria of the study. Descriptive statistics of age (years) of patient was also calculated in terms of mean and standard deviation. Mean age (years) in the study was 53.74+8.66 with ranges from 20 to 60 years. Distribution of gender of patient was also calculated in terms of frequency and percentage of male and female patients. There were 03 (1.8) male and 162 (98.2) female patients who were included in the study according to the inclusion criteria. Conclusion: The study concludes that elevated serum ferritin worsened liver injury. Hence it represents early marker for the severity of chronic liver disease, related both to the degree of liver fibrosis and to the necroinflammatory activity. Key Words: Chronic, Liver, Patients, Fibrosis.