International Journal of Gynecology & Obstetrics 58 (1997) 329-330 Brief communication Asymmetry of the labia minora, titerus didelphys, unilateral imperforate vagina and other miillerian anomalies A. Ruiz-Parra” , E. Barreto-Hauzeur, E. Angel-Miiller Depatiment of Obstettics and Gynecology, National Uniuersity of Colombia, Bogotd, Colombia Received 26 February 1997; revised 28 April 1997; accepted 8 May 1997 Keywords: Miillerian anomalies; Renal anomalies; Labia minora asymmetry The combination of uterus didelphys and uni- lateral imperforate vagina is a rare congenital anomaly. Patients will present symptomatic ipsi- lateral hematocolpos, hematometra and hematosalpinx [l]. In 1922 Purslow [2] reported the syndrome of uterus didelphys and obstructed hemivagina associated with ipsilateral renal agen- esis. We have studied five well-developed women with a marked asymmetry of the labia minora associated with this syndrome and with other miillerian anomalies. ECV, aged 32 years, had two previous sponta- neous abortions, a severe hypoplasia of the right labium minora; a longitudinal septum dividing the upper two thirds of the vagina, a blind ending at the right side and a normal cervix at the left side. Histerolaparoscopy revealed uterus didelphys with *Corresponding author. Departamento de Ginecologia y Obstetricia, Instituto Matemo Infantil, Carrera 10 No. l-66 Sur. (Piso 4), Bogot$ Colombia. Fax: +57 1 2460196, +57 1 2801637, +57 1 2337336. right hematocolpos. LAC, aged 14, had cyclic pelvic pain concomitant with the last six menses. She had severe hypotrophy of the left labium minora; there was a vagina of 7 cm length with a blind ending. The left anterolateral wall bulged into the vaginal lumen because of an hematocol- pos with hematometra. The pyelogram revealed left renal agenesis. LAC, aged 14, had cyclic pelvic pain during the last 12 months, she had an hypoplasia of the left labium minora, and absence of the vagina. She had a uterus didelphys; the right uterus was hypoplastic and the left one has hematometra; the cervix was absent. There was also a left hematosalpinx and endometriosis of the left ovary. The right fallopian tube and ovary were normal. The pyelogram revealed hypotrophy of the left kidney, bilateral dilation of the renal pelvis and ureter and vesicoureteral reflux. The renal gammagram revealed changes secondary to hydronephrosis but the renal function was nor- mal. AVS, aged 14, had episodic pelvic pain dur- ing 5 months; she had hypoplasia of the left 0020-7292/97/$17.00 0 1997 International Federation of Gynecology and Obstetrics PZZ SOO20-7292(97)00115-X