Vol.:(0123456789) 1 3 World Journal of Urology https://doi.org/10.1007/s00345-020-03518-z ORIGINAL ARTICLE HoLEP after prostate biopsy: does it have any impact? Sercan Yılmaz 1  · Engin Kaya 1  · Eymen Gazel 2  · Serdar Yalcın 1  · Halil Cagrı Aybal 3  · Mehmet Yılmaz 4  · Onur Açıkgöz 5  · Hakan Özdemir 6  · Lutf Tunc 7 Received: 10 August 2020 / Accepted: 30 October 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020 Abstract Purpose Holmium laser enucleation of the prostate (HoLEP) has recently become the recommended treatment for prostate in all sizes in benign prostate hyperplasia surgery. A recent prostate biopsy performed prior to the HoLEP procedure can make surgeons concerned about the surgery. We aimed to investigate the per- and postoperative outcomes of the HoLEP procedure in patients who underwent prostate biopsy and to evaluate the most appropriate surgery time after biopsy. Methods The data of 160 patients who underwent HoLEP by a single surgeon between March 2017 and December 2019 were retrospectively reviewed. The patients were divided into two groups, Group 1 consisted of 80 patients without prostate biopsy and Group 2 consisted of 80 patients with prior prostate biopsy. All HOLEP procedures in group 2 were performed at least 2 weeks following biopsy. Per- and postoperative outcomes, complications were evaluated. Results No signifcant diferences were found between groups in terms of by enucleation time, efciency of laser, efciency of enucleation, hospitalization time, and catheterization removal time. Only morcellation time was shorter in biopsy naïve patients. There were no statistical diferences in postoperative outcomes. Previous prostate biopsy did not afect the conti- nence status in our study group. There were not any Clavien grade 4 or higher complications. Urinary tract infection was higher in early post-biopsy period, there was no diference among the groups. Conclusıon Our study confrms that HoLEP is a safe and efcient surgical procedure for the patients with prior prostate biopsy. We believe that it can be safely performed 2nd week following prostate biopsy. Keywords HoLEP · Holmium laser · Prostate biopsy · Laser enucleation * Mehmet Yılmaz yilmazmehmet88@hotmail.com Sercan Yılmaz drsercanyilmaz@gmail.com Engin Kaya drenginkaya@yahoo.com Eymen Gazel eymen_gazel@yahoo.com Serdar Yalcın serdaryalcin@hotmail.com Halil Cagrı Aybal halilcagri@gmail.com Onur Açıkgöz dr.o.acikgoz@gmail.com Hakan Özdemir hozdemir@diason.info Lutf Tunc lutftunc@gmail.com 1 Department of Urology, Gulhane Training and Research Hospital, Health Sciences University, Ankara, Turkey 2 Department of Urology, Acıbadem University Ankara Hospital, Ankara, Turkey 3 Department of Urology, Kahramankazan Hamdi Eris State Hospital, Ankara, Turkey 4 Department of Urology, Zile State Hospital, Kahya Mahallesi Ata Caddesi No: 1 Zile, 60400 Tokat, Turkey 5 Department of Urology, Pendik State Hospital, Istanbul, Turkey 6 Department of Radiology, Diason Ultrasonography Center, Ankara, Turkey 7 Department of Urology, Gazi University School of Medicine, Ankara, Turkey