Research Article
Outcomes and National Trends for the Surgical Treatment of
Lumbar Spine Trauma
Doniel Drazin,
1
Miriam Nuno,
1
Faris Shweikeh,
1,2
Alexander R. Vaccaro,
3
Eli Baron,
1
Terrence T. Kim,
4
and J. Patrick Johnson
1,5
1
Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
2
Department of Surgery, University of Arizona College of Medicine, Tucson, AZ 85724, USA
3
Department of Orthopedic Surgery, Tomas Jeferson University, Philadelphia, PA 19107, USA
4
Department of Orthopedics, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA
5
Department of Neurosurgery, University of California Davis Medical Center, Sacramento, CA 95820, USA
Correspondence should be addressed to Doniel Drazin; ddrazin@gmail.com
Received 13 February 2016; Revised 21 May 2016; Accepted 22 May 2016
Academic Editor: Panagiotis Korovessis
Copyright © 2016 Doniel Drazin et al. Tis is an open access article distributed under the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Introduction. Operative treatment of lumbar spine compression fractures includes fusion and/or cement augmentation. Our aim
was to evaluate postoperative diferences in patients treated surgically with fusion, vertebroplasty, or kyphoplasty. Methods. Te
Nationwide Inpatient Sample Database search for adult vertebral compression fracture patients treated 2004–2011 identifed 102,316
surgical patients: 30.6% underwent spinal fusion, 17.1% underwent kyphoplasty, and 49.9% underwent vertebroplasty. Univariate
analysis of patient and hospital characteristics, by treatment, was performed. Multivariable analysis was used to determine factors
associated with mortality, nonroutine discharge, complications, and patient safety. Results. Average patient age: fusion (46.2),
kyphoplasty (78.5), vertebroplasty (76.7) ( < .0001). Gender, race, household income, hospital-specifc characteristics, and
insurance diferences were found ( ≤ .001). Leading comorbidities were hypertension, osteoporosis, and diabetes. Risks for higher
mortality (OR 2.0: CI: 1.6–2.5), nonroutine discharge (OR 1.6, CI: 1.6–1.7), complications (OR 1.1, CI: 1.0–1.1), and safety related
events (OR 1.1, CI: 1.0–1.1) rose consistently with increasing age, particularly among fusion patients. Preexisting comorbidities and
longer in-hospital length of stay were associated with increased odds of nonroutine discharge, complications, and patient safety.
Conclusions. Fusion patients had higher rates of poorer outcomes compared to vertebroplasty and kyphoplasty cohorts. Mortality,
nonroutine discharge, complications, and adverse events increased consistently with older age.
1. Introduction
Lumbar compression fractures are among the most com-
mon medical and surgical conditions encountered by spinal
surgeons [1]. Approximately 1.4 million patients sustain
vertebral compression fractures every year [2], with an annual
inpatient cost just under $5 billion [3]. Compression fractures
disproportionately afect the elderly (65+ years) secondary
to osteoporosis, which is responsible for >700,000 spinal
fracture cases in the United States annually [4]. Although
traumatic lumbar fractures represent a small portion in
all trauma patients, their physical and fnancial burden on
patients are more signifcant than other injuries [5].
Standard treatment of vertebral compression fractures
consists of conservative management, including bed rest,
bracing, and analgesics [6]. Studies, however, have noted
that these practices are ofen insufcient in improving pain
and mobility of these patients [7–9]. Operative interventions,
namely, surgical fusion with instrumentation and cement
augmentation procedures, have been gaining popularity [10,
11] as studies have shown both short-term physical improve-
ments [12–14] and long-term survival benefts [15, 16] in select
patients undergoing surgical intervention for compression
fractures.
Numerous studies have looked at national trends and
outcomes of cement augmentation procedures (vertebro-
plasty and kyphoplasty) for vertebral compression fractures
[13, 15–18]. Tese studies, however, do not evaluate difer-
ences in demographics and outcomes among surgical fusion,
Hindawi Publishing Corporation
BioMed Research International
Volume 2016, Article ID 3623875, 9 pages
http://dx.doi.org/10.1155/2016/3623875