10–14 October 2010, Prague, Czech Republic Oral communication abstracts on the pain during insertion, in the following 3 days and at 4 to 6 weeks. Methods: A prospective cohort of 331 women in whom a Mirena was inserted. At the day of insertion they completed a first questionnaire including a pain assessment score from 0 to 10. A second questionnaire was handed to them to record pain experienced in the following 3 days and in the last 14 days before routine follow- up ultrasound 6 weeks after insertion. At ultrasound the position of the uterus was recorded and the position of the Mirena was assessed with 2D- and 3D-imaging. The sonographer was blinded as to the answers to the questionnaire. The pain scores were compared to the ultrasound findings. The first 93 3D-volumes were also examined off-line to determine if the arms extended past the confines of the endometrial cavity. This was reported as ‘embedded’ (Benacerraf et al. UOG 2009;34:110–6). Results: The mean (SD) pain-score at insertion was 4.5 (2.6) versus 2.7 (2.7) in the first 3 days and 0.8 (1.7) 4 to 6 weeks after insertion. The uterus was anteflexed in 80% of cases, retroflexed in 17%, stretched in 2.5% and mobile in 0.5%. The localization of the Mirena stem was recorded as abnormal in 7.1% of cases and the arms were abnormally unfolded in another 3.4%. The right arm was considered embedded in 56.8% and the left arm in 56.3%. The position the uterus and of the LNG-IUS (both of the stem and of the arms) did not influence the pain scores, nor did the fact that the IUD arms were considered embedded on coronal 3D-volume reconstruction. Conclusions: The position of the uterus, the position of the LNG-IUS nor the ultrasound image that the IUS arms were embedded, did influence the pain score at insertion, in the first 3 days or at 4 to 6 weeks after insertion. Pain does not seem to be a reliable predictor of correct position. A routine ultrasound check seems therefore recommended 6 weeks after Mirena insertion. OC10.04 Can we predict posterior compartment deep infiltrative endometriosis using sonovaginography in women undergoing laparoscopy for chronic pelvic pain? S. Reid , M. Mongelli, J. Riemke, T. Bignardi, I. V. Casikar, D. Alhamdan, G. Reid, G. Condous Nepean Hospital, Penrith, NSW, Australia Objectives: To use sonovaginography (SVG) to predict posterior compartment deep infiltrative endometriosis (DIE) in women undergoing laparoscopy for chronic pelvic pain. Methods: This is a continuing, prospective observational study, which began in June 2009. All women included in this study were of reproductive age, had history of chronic pelvic pain, and had a plan for laparoscopic endometriosis surgery. A history was obtained and SVG was performed on all women prior to laparoscopy. During SVG, a transvaginal (TV) ultrasound was performed with the introduction of gel into the posterior fornix of the vagina. The gel created an acoustic window between the TV probe and the surrounding structures of the vagina, allowing for visualization of the posterior compartment. SVG was then used to predict posterior compartment DIE. Women underwent laparoscopic surgery for diagnosis and, if necessary, surgical treatment of endometriosis. The correlation between SVG findings and laparoscopic findings was then analysed to assess the ability of SVG to predict posterior compartment DIE. Results: To date, complete SVG and laparoscopic data was available for 21 women. The sensitivity and specificity for SVG in the prediction of posterior compartment DIE, as defined as rectovaginal, retrocervical and rectosigmoid nodules, were 80% and 100%, respectively. The PPV and NPV were 100% and 94%, respectively. When SVG was used to predict DIE in both midline (i.e. rectovaginal, retrocervical and rectosigmoid nodules) and lateral regions (i.e. uterosacral ligaments), the sensitivity and specificity were 45% and 100% respectively. The PPV and NPV were 100% and 63%, respectively. Conclusions: SVG appears to be more effective in predicting DIE in the midline posterior compartment in comparison to lateral regions. SVG provides additional diagnostic information to conventional pelvic sonography, which may allow for the planning of specific endometriosis surgery and the need for colorectal input. OC10.05 Can we predict pouch of Douglas obliteration using sonovaginography in women with chronic pelvic pain? S. Reid , M. Mongelli, J. Riemke, T. Bignardi, I. Casikar, D. Alhamdan, G. Reid, G. Condous Nepean Hospital, Penrith, NSW, Australia Objectives: To use sonovaginography (SVG) to predict pouch of Douglas obliteration in women with chronic pelvic pain, prior to endometriosis surgery. Methods: This is a continuing, prospective observational study, which began in June 2009. All women included in this study were of reproductive age, had history of chronic pelvic pain, and had a plan for laparoscopic endometriosis surgery. A history was obtained and an ultrasonographic evaluation with sonovaginography (SVG) was performed on all women prior to laparoscopy. During SVG, a transvaginal (TV) ultrasound was performed with the introduction of gel into the posterior fornix of the vagina. The gel created an acoustic window between the TV probe and the surrounding structures of the vagina, allowing for visualization of the pouch of Douglas (POD). Women then underwent laparoscopic surgery for diagnosis and, if necessary, surgical treatment of endometriosis. The correlation between SVG findings and laparoscopic findings was then analysed to assess the ability of SVG to predict obliteration of the POD prior to surgery. Results: To date, complete SVG and laparoscopic data was available for 21 women. For predicting POD obliteration, the sensitivity and specificity of SVG were 83% and 100%, respectively. The PPV and NPV were 100% and 94%, respectively. Conclusions: Although the numbers are small, this ongoing study demonstrates that SVG can predict POD obliteration. This has potential implications for the selection of women for specialist advanced laparoscopic intervention. OC11: NEW IMAGING TECHNIQUES OC11.01 Placental and fetal oxygenation assessment in a rat model of intra uterine growth restriction with BOLD contrast in MRI A. Sabine 1,2 , B. Deloison 1,2 , S. Nathalie 2,3 , C. Charles-Andre 2,3 , Y. Ville 1,2 , C. Olivier 2,3 , L. J. Salomon 1,2 1 Assistance Publique-H ˆ opitaux de Paris, H ˆ opital Necker Enfants Malades, Paris, France; 2 INSERM, U970, Paris Cardiovascular Research Center - PARCC, Paris, France; 3 Assistance Publique-H ˆ opitaux de Paris, H ˆ opital Europ´ een Georges Pompidou, Paris, France Objectives: We sought to non-invasively evaluate placental and fetal oxygenation in a rat model of intrauterine growth restriction (IUGR) using blood oxygen level-dependant (BOLD) contrast imaging. Methods: Twenty-four rats at 16 days of gestation underwent surgical ligation of the left uterine vessel to induce IUGR in the left uterine horn. In 22 rats, the signal intensity of maternal liver, healthy and pathological foeto-placental units before and after maternal hyperoxygenation were measured at day 20 of gestation using a balanced steady state free precession (balanced-SSFP) sequence on a 1.5T system. Results: Mean weight of fetuses was 4.32 ± 0.66 g vs. 3.49 ± 0.56 g in the right vs. left uterine horn (P < 0.001). Under hyperoxygenation an increase of BOLD signal intensity was observed in liver (+12%, Ultrasound in Obstetrics & Gynecology 2010; 36 (Suppl. 1): 1–51 19