© The Author(s) 2023. Published by Oxford University Press on behalf of FEMS. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com ORIGINAL UNEDITED MANUSCRIPT Whole genomes of deep-sea sponge-associated bacteria exhibit high novel natural product potential Poppy J. Hesketh-Best 1*$ , Grant G. January 2* , Matthew J. Koch 2* , Philip J. Warburton 2 , Kerry L. Howell 1 , Mathew Upton 2† 1 School of Biological and Marine Sciences, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK 2 School of Biomedical Sciences, University of Plymouth, Drake Circus, Plymouth PL4 8AA, UK. * These authors contributed equally to the publication † Corresponding author - Mathew Upton: mathew.upton@plymouth.ac.uk $ Current address: College of Veterinary Medicine, University of Minnesota, Saint Paul, US Downloaded from https://academic.oup.com/femsmicrobes/advance-article/doi/10.1093/femsmc/xtad005/7051222 by guest on 24 February 2023