Open Journal of Medical Microbiology, 2022, 12, 156-167 https://www.scirp.org/journal/ojmm ISSN Online: 2165-3380 ISSN Print: 2165-3372 DOI: 10.4236/ojmm.2022.124014 Dec. 29, 2022 156 Open Journal of Medical Microbiology Prevalence of Extended Spectrum Beta-Lactamase-Producing Escherichia coli in Broiler Chickens in Yaoundé Capital City of Cameroon Cecile Ingrid Djuikoue 1* , Charlène Nkouankou Tomi 1 , Cedric Seugnou Nana 1 , Müller Fotsac 1 , Moffo Frédéric 2 , Willy Yamdeu Djonkouh 1 , Andrea Tchouotou Didi 1 , Cedric Ngalani Toutcho 3 , Abel Wade 4 , Venant Tchokonte-Nana 1 1 Higher Institute of Health Sciences, Université des Montagnes, Bangangté, Cameroon 2 Department of Pharmacy, Pharmacology and Toxicology, School of Veterinary Medicine and Sciences, University of Ngaoudéré, Ngaoundéré, Cameroon 3 Faculty of Medicine and Pharmaceutical Science, University of Douala, Douala, Cameroon 4 National Veterinary Laboratory, Ministry of Livestock, Fisheries and Animal Industries, Yaoundé, Cameroon Abstract Background: Escherichia coli are ubiquitous bacteria colonising both hu- mans and animals. Extended spectrum β-lactamase-producing E. coli has been selected as a suitable indicator for the monitoring and surveillance of antimicrobial resistance. Death due to resistant bacteria is continuously rising in Cameroon, but the contribution of the aviary sector is not well studied. Therefore, this study aimed to investigate the resistance profile of extended spectrum beta-lactamases-producing Escherichia coli strains, isolated from faeces of broiler chickens in Yaoundé, capital city of Cameroon. Methods: A cross-sectional descriptive study was carried out from February to June 2020. Escherichia coli were isolated from samples of broilers in poultry farms in Yaoundé and submitted to the extended spectrum β-lactamase screening. The logistic regression was used to assess the statistical association of a signific- ance threshold p-value of 0.05. Results: Out of 385 faecal samples collected in broiler farms, 114 Escherichia coli isolates were obtained out of which 30 (26.32%) were Extended Spectrum Beta-Lactamases-producing Escherichia coli. These isolates revealed high resistance to all antibiotic families. Poor storage conditions for feeds and the proximity to latrines, the troughs on the ground, the lack of foot bath and uniforms, the inadequate treatment of faec- How to cite this paper: Djuikoue, C.I., Tomi, C.N., Nana, C.S., Fotsac, M., Frédéric, M., Djonkouh, W.Y., Didi, A.T., Toutcho, C.N., Wade, A. and Tchokonte-Nana, V. (2022) Beta-Lactamase-Producing Escheri- chia coli in Broiler Chickens in Yaoundé Capital City of Cameroon. Open Journal of Medical Microbiology, 12, 156-167. https://doi.org/10.4236/ojmm.2022.124014 Received: September 29, 2022 Accepted: December 26, 2022 Published: December 29, 2022 Copyright © 2022 by author(s) and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Open Access