Journal Pre-proof Role of tau protein in Alzheimer's disease: The prime pathological player Shibi Muralidar, Senthil Visaga Ambi, Saravanan Sekaran, Diraviyam Thirumalai, Balamurugan Palaniappan PII: S0141-8130(20)34086-1 DOI: https://doi.org/10.1016/j.ijbiomac.2020.07.327 Reference: BIOMAC 16375 To appear in: International Journal of Biological Macromolecules Received date: 25 April 2020 Revised date: 7 July 2020 Accepted date: 31 July 2020 Please cite this article as: S. Muralidar, S.V. Ambi, S. Sekaran, et al., Role of tau protein in Alzheimer's disease: The prime pathological player, International Journal of Biological Macromolecules (2020), https://doi.org/10.1016/j.ijbiomac.2020.07.327 This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2020 Published by Elsevier.