Original article Application of continuous passive motion in patients with distal radius fractures: A randomized clinical trial Utilisation d’un arthromoteur passif continu chez les patients avec une fracture de l’extre ´mite ´ distale du radius: essai clinique randomise ´ A. Shirzadi a , M. Farzad a,b, *, A.R. Farhoud c , E. Shafiee b a Occupational Therapy, University of Social Welfare and Rehabilitation Sciences, Daneshjoo Blvd, Tehran, Iran b Physical therapy, University of Western Ontario, London, Ontario, Canada c Orthopedic Surgery, Imam Hospital Complex, Tehran University of Medical Sciences, Joint Reconstruction Research Center, Iran Hand Surgery and Rehabilitation xxx (2020) xxx–xxx * Corresponding author. E-mail addresses: ashirzadi71@gmail.com (A. Shirzadi), mfarzad@uwo.ca (M. Farzad), am_farhoud@yahoo.com (A.R. Farhoud), eshafiee@uwo.ca (E. Shafiee). A R T I C L E I N F O Article history: Received 3 May 2020 Received in revised form 29 July 2020 Accepted 3 August 2020 Available online xxx Keywords: Distal radius fracture Pain PRWHE CPM Continuous passive motion Mots-cle ´s: Fracture de l’extre ´ mite ´ distale du radius Douleur PRWHE CPM Mobilisation passive continue A B S T R A C T The aim of this study was to know if applying continuous passive motion (CPM) in addition to routine exercises is more effective than routine exercises alone in pain reduction, range of motion (ROM) and function improvement after distal radius fractures (DRFs). In this randomized controlled trial, 21 patients with non-stabilized DRF after pin removal were randomly assigned to experimental and control groups. The experimental group received stretching exercises with CPM machine for 2  15 min per session. Both groups received routine exercises for 1 h, three times a week for 4 weeks. The primary outcome measure was pain evaluated on a visual analog scale (VAS), and the secondary outcome measures were disability evaluated by the patient-rated wrist/hand evaluation and ROM (goniometry) at 4, 6, and 12 weeks. Univariate analysis of covariance (ANCOVA) and a one-way repeated measure mixed model analysis of variance (ANOVA) were used for data analysis. Twenty-one participants completed the 12-week follow-up. Pain relief, ROM and functional improvement revealed that the treatment was successful in both groups. We detected no significant differences (p > 0.05) between the two groups at the end of the follow-up period regarding pain, ROM, and function. Using a CPM machine had no additional effect on pain reduction, ROM and function improvement compared with routine exercises in patients with DRF.  C 2020 SFCM. Published by Elsevier Masson SAS. All rights reserved. R E ´ S U M E ´ Le but de cette e ´ tude e ´ tait de savoir si l’utilisation d’un arthromoteur passif continu (APC) en plus d’exercices pratiques e ´ tait plus efficace que des exercices pratiques seuls dans la re ´ duction de la douleur, l’amplitude des mouvements et l’ame ´ lioration des fonctions apre `s une fracture de l’extre ´ mite ´ distale du radius (EDR). Dans cet essai contro ˆle ´ randomise ´, 21 patients avec une fracture de l’EDR non stabilise ´e apre `s le retrait des broches ont e ´ te ´ affecte ´s au hasard au groupe intervention et au groupe contro ˆle. Le groupe intervention a rec ¸u des exercices d’e ´ tirement avec un APC pendant 2 x 15 minutes par session. Les deux groupes ont rec ¸u des exercices de routine pendant une heure trois fois par semaine pendant quatre semaines. Le crite ` re de jugement principal e ´ tait la douleur e ´ value ´e par l’e ´ chelle visuelle analogique (EVA) et les crite ` res de jugements secondaires e ´ taient l’incapacite ´e ´ value ´e par l’e ´ valuation du poignet et de la main par le patient (PRWHE) et l’amplitude des mouvements (goniome ´ trie) a ` 4, 6 et 12 semaines. Une analyse de variance univarie ´e (ANCOVA) et une analyse de variance a ` mode ` le mixte a ` mesure re ´pe ´te ´e unidirectionnelle (ANOVA) ont e ´ te ´ utilise ´ es pour l’analyse des donne ´ es. Vingt-et-un participants ont effectue ´ un suivi de 12 semaines. Le soulagement de la douleur, l’amplitude des mouvements et l’ame ´ lioration de la fonction ont montre ´ que le traitement e ´ tait efficace dans les deux G Model HANSUR-1159; No. of Pages 6 Please cite this article in press as: Shirzadi A, et al. Application of continuous passive motion in patients with distal radius fractures: A randomized clinical trial. Hand Surg Rehab (2020), https://doi.org/10.1016/j.hansur.2020.08.001 Available online at ScienceDirect www.sciencedirect.com https://doi.org/10.1016/j.hansur.2020.08.001 2468-1229/  C 2020 SFCM. Published by Elsevier Masson SAS. All rights reserved.