Acta Scientific Orthopaedics (ISSN: 2581-8635) Volume 6 Issue 2 February 2023 Calcitonin Protocol Therapy for a Treatment of a Bone Giant Cell Tumor in Childhood: A Case Report Khaled Kamoun 1 *, Imed Mdhafer 1 , Khaled Khelil 1 , Faten Farah 2 and Mourad Jenzri 1 1 Pediatric Orthopedics Department, KASSAB Institute, El Manar University Tunis 2 Pathology Department, KASSAB Institute, El Manar University Tunis *Corresponding Author: Khaled Kamoun, Pediatric Orthopedics Department, KASSAB Institute, El Manar University Tunis. Case Report Received: December 06, 2022 Published: January 13, 2023 © All rights are reserved by Khaled Kamoun., et al. Abstract Keywords: Giant Cell Tumors; Pediatrics; Calcitonin; Tumor Giant cell tumors (GCTs) are rare tumors and represent 5 to 10% of all primary bone tumors. Those tumors are rare before skeletal maturity (1.7-2.5%). They appear as an expansile lytic lesions involving the metaphyso-epiphyseal area of long bones. We report a metaphyso-epiphyseal upper tibia location in a 13-year-old boy treated by curettage followed by calcitonin protocol injections with 13 years follow-up. Skeleton GCTs are highly uncommon in pediatric age group. Calcitonin therapy for GCTs in children has not been reported in the literature. This protocol can be an interesting alternative treatment for these tumor locations. Introduction Giant cell tumors (GCTs) are almost benign and usually occur at the epiphyso-metaphyseal level of long bones in young adults. Its location in a child remains exceptional. We report the case of 13-year-old child complained of pain and swelling in the proximal tibia. MRI followed by core surgical biopsy confirmed a giant cell tumor diagnosis which is quite rare in this age group. Many thera- peutic procedures were already reported and curettage was the most procedure performed in adult and leads often to tumor re- currence. We report a calcitonin treatment protocol case treating such bone tumor location. Case Report We report a case of a 13-year-old boy treated conservatively during two months for a pathological fracture of the upper ex- tremity of the right tibia on a well-defined lytic image, taken for unicameral bone cyst (Figure 1). The evolution was marked by the extension of the lytic image questioning about the initial diagnosis (Figure 2). The patient was admitted for the evaluation and further man- agement of his complains. There was no soft tissue involvement, although the overlying skin was warm. No appreciable lymphade- nopathy was noted. Figure 1: Pathological fracture on expansile lytic lesion. Figure 2: Radiographic aspect after 45 days of cast immobilization. DOI: 10.31080/ASOR.2023.06.0682 Citation: Khaled Kamoun., et al. “Calcitonin Protocol Therapy for a Treatment of a Bone Giant Cell Tumor in Childhood: A Case Report”. Acta Scientific Orthopaedics 6.2 (2023): 37-40.