Research Artcle Ment Health Fam Med (2018) 14: 665-669 2018 Mental Health and Family Medicine Ltd Obstructive Sleep Apnea and Psychiatry Disorders Salim R Surani Clinical Associate Professor , University of North Texas, Aransas Pass, TX, 78366, United States Wendy Garcia Research Associate, Dorrington Medical Associates, Houston, USA Sara Surani Harvard University, Boston, MA USA Joseph Varon, MD, FACP, FCCP, FCCM, FRSM Clinical Professor of Medicine. The University of Texas Medical Branch at Galveston, Houston, TX, 77030, United States. ABSTRACT The prevalence of Obstructive Sleep Apnea (OSA) has increased remarkably during last twenty years, 60.6% of men and 36.9% of women from 50-70 years old have been diagnosed with OSA, the relevance of this pathology remains in the comorbidities associated with it, one that has not been studied deeply is psychiatric disorders, that have negatively afected the life of patients with OSA. Five main disorders were reviewed according to latest data from 1983 to 2016 on Bipolar Disorder, Dementia, Insomnia, Psychosis, and Attention defcit hyperactivity disorder. For some of this illness the symptomatology is very similar to the ones experienced in OSA, such as sleep deprivation, daytime sleepiness and cognitive impairment and their treatment is difcult due to poor compliance. Recent studies have shown that treatment of OSA with CPAP or surgery has a positive impact in decreasing psychiatric symptoms, four out of the fve pathologies reviewed had remarkable improvement of psychiatric symptomatology, ADHD, Insomnia, Psychosis and Dementia. In bipolar disorder the results are not conclusive because there are some reports that stated that CPAP actually increased the risk of mania episodes, however in this particular illness the risk factors in common with OSA are less that the rest of psychiatric disorders reviewed. Core tip: OSA prevalence has been increasing along with the aging population, and the comorbidity with psychiatric disorders needs to be evaluated in order to have a complete approach with better outcomes. The symptomatology on this pathologies may overlap, but the treatment in four out of the fve disorders reviewed have a positive outcome in psychiatric symptoms after treatment with CPAP or surgery. OSA may be undiagnosed in this population and this results show the importance of early diagnosis, to improve quality of life in this patients. Keyword: Obstructive Sleep Apnea; Insomnia; Bipolar Disorder; Dementia; Psychosis; Attention defcit hyperactivity disorder. quality of life of OSA patients, and the prevalence of OSA in serious mental disorders has been reported to be 25.7%, of those, the most frequent was major depressive disorder 36.3% followed by bipolar disorder 24.5% [4,5]. In this review we evaluate the efect of OSA treatment in psychiatric conditions such as Bipolar Disorder, Dementia, Insomnia, Psychosis, and Attention defcit hyperactivity disorder (ADHD). Bipolar disorder (BD) is a debilitating condition and is characterized by episodes of mania, hypomania and major depression [6]. The prevalence of BD is highly variable depending on the inclusion criteria and defnition use by every author, Hattori reported 69% meanwhile Levine reported just Introducton Obstructive sleep apnea (OSA) is a condition characterized by repetitive partial (hypopnea) or complete (apnea) upper airway obstruction during sleep [1]. During the last twenty years there is data that suggested there has been an increase in psychological conditions among individuals with OSA [2,3]. The importance of these pathologies are based in their fast increase rate, the prevalence of OSA in the general population in 1993 was estimated at 3 to 7% of adult men and 2 to 5% of adult women, twenty years later is around 36.1% in men and 14% in women between 30-49 years and up to 60.6% and 36.9% respectively in people from 50-70 years [2,3]. The comorbidity of psychiatric disorders has reported to negatively afect the