Case Report
Minimally Invasive Treatment of Mirizzi Syndrome, a Rare
Cause of Cholestasis in Childhood
Ahmet Ali Tuncer,
1
Sezgin Yilmaz,
2
Mustafa Yavuz,
2
and Salih ÇetinkurGun
1
1
Department of Pediatric Surgery, Afyon Kocatepe University Hospital, Afyonkarahisar, Turkey
2
Department of General Surgery, Afyon Kocatepe University Hospital, Afyonkarahisar, Turkey
Correspondence should be addressed to Ahmet Ali Tuncer; drtaali@yahoo.com
Received 31 July 2016; Accepted 4 October 2016
Academic Editor: Larry A. Rhodes
Copyright © 2016 Ahmet Ali Tuncer et al. Tis is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly
cited.
Mirizzi syndrome is the compressive blockage of the cystic or choledochal duct caused by a biliary stone occupying the cystic canal
or Hartmann’s pouch. Tis occurrence is rare and, in English literature, three cases defned in children have been observed. In
order to draw attention to this rare occurrence, we preferred a 14-year-old male patient with Mirizzi syndrome. In this case, ERCP
was performed preoperatively and the diagnosis was carried out with the help of clear visualisation and identifcation of the tissue
structures as well as the stent placed in bile duct; so we protected the patient from the possible iatrogenic injury occurring during
surgery.
1. Introduction
Mirizzi syndrome is the compressive blockage of the cystic
or choledochal duct caused by a biliary stone occupying the
cystic canal or Hartmann’s pouch. It was frst described in
1948 by Mirizzi [1], clinically characterized by intermittent
or persistent obstructive jaundice. It is more common in
patients with cholelithiasis for a long time and women [2].
Tere are three cases defned in children in English literature
[3–5]. Factors that make this patient population special is
the difculty in preoperative diagnosis and treatment, with
an additional high risk of iatrogenic damage to the biliary
system. In order to draw attention to this rare occurrence, we
preferred a 14-year-old male patient with Mirizzi syndrome.
2. Case Presentation
A fourteen-year-old male patient applied to our clinic with a
1-week history of right upper quadrant pain and icteric sclera.
Physical examination revealed the tenderness on Murphy’s
point and jaundice extending down to the body. Labora-
tory examinations were consistent with obstructive jaundice
(aspartate aminotransferase: 141 U/L, alanine aminotrans-
ferase: 230 U/L, gamma-glutamyl transpeptidase: 219, total
bilirubin: 7.81 mg/dL, conjugated bilirubin: 7.4 mg/dL, white
blood cell: 12.1 × 10
3
/L, and neutrophil: 8.9 × 10
3
/L). Afer
ultrasonography was performed on the patient that revealed
cholelithiasis and cholestasis, endoscopic retrograde cholan-
giopancreatography (ERCP) was planned. During ERCP, it
seemed that the cystic duct is quite weak and inside Hart-
mann’s pouch compressed the choledoc flled with stones.
Sphincterotomy was carried out. Afer the choledochal canals
were cleaned, a choledochal stent was replaced (Figure 1).
Laparoscopic cholecystectomy was carried out a day later.
During laparoscopy, choledochal compression caused by
Hartmann pouch was clearly seen (Figure 2). Te patient was
discharged afer being observed to have normal postoperative
bilirubin values. Choledochal stent was taken by endoscopy
on the frst postoperative month. In Mirizzi syndrome since
the gallbladder compresses the choledochus and eventually
causes obstructive jaundice, it should be removed. Since
the patient was admitted with cholecystitis and obstructive
jaundice, a preoperative ERCP should be planned in order
to normalize the jaundice and clarify the etiology as in
our patient. An immediate laparoscopic cholecystectomy
should be planned just afer the ERCP. Cholecystectomy was
carried out under general anesthesia but endoscopies were
Hindawi Publishing Corporation
Case Reports in Pediatrics
Volume 2016, Article ID 8940570, 3 pages
http://dx.doi.org/10.1155/2016/8940570