Accepted Manuscript Piperazine-Azole-Fluoroquinolone Hybrids: Conventional and Microwave Ir- radiated Synthesis, Biological Activity Screening and Molecular Docking Stud- ies Arif Mermer, Ozlem Faiz, Ahmet Demirbas, Neslihan Demirbas, Manikandan Alagumuthu, Sivakumar Arumugam PII: S0045-2068(18)30841-1 DOI: https://doi.org/10.1016/j.bioorg.2019.01.009 Reference: YBIOO 2713 To appear in: Bioorganic Chemistry Received Date: 6 August 2018 Revised Date: 1 January 2019 Accepted Date: 6 January 2019 Please cite this article as: A. Mermer, O. Faiz, A. Demirbas, N. Demirbas, M. Alagumuthu, S. Arumugam, Piperazine-Azole-Fluoroquinolone Hybrids: Conventional and Microwave Irradiated Synthesis, Biological Activity Screening and Molecular Docking Studies, Bioorganic Chemistry (2019), doi: https://doi.org/10.1016/j.bioorg. 2019.01.009 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.