S1 Tröger’s Base Chemistry in Solution and in Zr(IV)- Based Metal-Organic Frameworks Wei Gong, †,‡ Masoud Kazem-Rostami, ‡ Florencia A. Son, ‡ Shengyi Su, ‡ Kira M. Fahy, ‡ Haomiao Xie, ‡ Timur Islamoglu, ‡ Yan Liu, † J. Fraser Stoddart, ‡, ⊥ , △ , ‖ Yong Cui, *,† and Omar K. Farha *,‡,# † School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, China ‡ Department of Chemistry and International Institute for Nanotechnology (IIN), Northwestern University, Evanston, Illinois 60208, United States # Department of Chemical & Biological Engineering, Northwestern University, Evanston, Illinois 60208, United States ⊥ School of Chemistry, University of New South Wales, Sydney, NSW 2052, Australia △ Stoddart Institute of Molecular Science, Department of Chemistry, Zhejiang University, Hangzhou 310021, China ‖ ZJU-Hangzhou Global Scientific and Technological Innovation Center, Hangzhou 311215, China * Corresponding authors: yongcui@sjtu.edu; o-farha@northwestern.edu