Received: 19 February 2017 Revised: 20 August 2017 Accepted: 21 September 2017 DOI: 10.1002/jclp.22561 RESEARCH ARTICLE Daily hassles score associates with the somatic and psychological health of patients with Crohn's disease Orly Sarid 1 Vered Slonim-Nevo 1 Ruslan Sergienko 1 Avihu Pereg 1 Elena Chernin 1 Terri Singer 1 Dan Greenberg 1 Doron Schwartz 2 Hillel Vardi 1 Michael Friger 1 Shmuel Odes on behalf of the Israel IBD Research Nucleus (IIRN) 1 1 Ben-Gurion University of the Negev 2 Soroka Medical Center Correspondence Shmuel Odes, MD, AGAF, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 653, Beer Sheba 84105, Israel. Email: odes@bgu.ac.il Funding information This work was supported by a generous grant from The Leona M. and Harry B. Helmsley Char- itable Trust. We report no financial conflicts of interest. Abstract Objective To examine the associations of daily hassles with the somatic and psychological health of Crohn's disease (CD) patients. Method A cross-sectional study of 400 self-selected adult CD patients was performed with completion of demographic, medical, and psychosocial questionnaires: economic status; Patient Harvey- Bradshaw Index of disease activity; Daily Hassles Scale (DHS); Short Inflammatory Bowel Disease Questionnaire (SIBDQ) and Short- Form Health Survey (SF-36 Physical and Mental Health) quality of life measures; Brief Symptom Inventory of psychological stress with summary Global Severity Index (GSI); Family Assessment Device; and List of Threatening Life Experiences. Analyses included correla- tions, regressions, and Sobel test statistic. Results The patients were aged 38.7 ± 14.1 years, 61% female and 67% working. The Patient Harvey-Bradshaw Index was 5.52 ± 4.87. The DHS was 88.0 ± 23.2, similar in men and women, higher in smokers, and increased with greater disease activity (p < .001). The most commonly reported hassles were time, social, and work. DHS had significant negative correlations with age, disease dura- tion, and economic status and positive correlations with GSI, SF-36, and SIBDQ. An increased Daily Hassles score was associated with reduced SIBDQ (p < .001) and SF-36 Mental Health (p < .001) and increased GSI (p < .001) and Patient Harvey-Bradshaw Index (p < .001). This effect of DHS on Patient Harvey-Bradshaw Index was mediated by GSI (Sobel t = 6.09, p < 0.001). J. Clin. Psychol. 2017;1–20. wileyonlinelibrary.com/journal/jclp c  2017 Wiley Periodicals, Inc. 1