ORIGINAL ARTICLE Journal of Evolution of Medical and Dental Sciences/ Volume 2/ Issue 45/ November 11, 2013 Page 8869 A STUDY OF SPIROMETRIC LUNG FUNCTION TETS AND ITS CORRELATION WITH HIGH RESOLUTION COMPUTED TOMOGRAPHY IN PATIENTS OF RHEUMATOID ARTHRITIS Dinesh Kumar 1 , Devinder Mahajan 2 , Harkirat Kaur 3 , C L Thukral 4 , Sunil Grover 5 HOW TO CITE THIS ARTICLE: Dinesh Kumar, Devinder Mahajan, Harkirat Kaur, CL Thukral, Sunil Grover. “A study of spirometric lung function tets and its correlation with high resolution computed tomography in patients of rheumatoid arthritis”. Journal of Evolution of Medical and Dental Sciences 2013; Vol. 2, Issue 45, November 11; Page: 8869-8873. ABSTRACT: Rheumatoid arthritis is disease which usually starts as an insidious symmetrical polyarthritis often with non specific systemic symptoms. Pleuropulmonary involvement is a important cause of morbidity and mortality in patients of rheumatoid arthritis. The extra articular manifestations like bronchiectasis, interstitial lung disease, caplan syndrome are well known complications of rheumatoid arthritis 1 . To make these things more clear, the present study has was conducted enrolling 50 patients of rheumatoid arthritis coming to Medicine Department of Sri Guru Ram Das Institute of Medical Sciences and Research, Vallah, Sri Amritsar. RESULTS: In this study it was found that bronchiectasis and reticulonodular pattern were the most common findings on High resolution computed tomography accounting for 18 %. On spirometry restrictive pattern dominated over obstructive pattern in this study. On HRCT also the restrictive pattern was the most common finding. The results of both were correlated using spearman formula and the results were statistically significant with p value of <0.05. Even the finding of both spirometry and HRCT were correlated with duration of disease and it was found that restrictive pattern dominates over obstructive with increasing duration of disease (from <5 years to > 10 years) and the correlation was statistically significant with p value of <0.05. INTRODUCTION: Rheumatoid arthritis is a chronic inflammatory systemic disease that produces most of its manifestations in diarthrodial joints. The most common form of disease is demonstrated by symmetrical, destructive and deforming polyarthritis affecting small and large synovial joints with associated systemic disturbances in addition to variety of extra-articular features and presence of circulating antiglobulin antibodies. The prevalence of RA worldwide is 0.3 to 1.5%. It is more common in females with ratio of 2:1 2 AIMS AND OBJECTIVES: To correlate spirometric lung function tests with HRCT findings in patients of rheumatoid arthritis and to correlate these findings with duration of disease. MATERIAL AND METHODS: 50 patients of rheumatoid arthritis in SGRDIMSR, Sri Amritsar. Patients divided into three groups < 5 years, 5 to 10 years and >10 years based on duration of disease. Spirometric function tests: By Spiro Excel Equipment HRCT findings: By SEIMENS SOMATOM EMOTION Equipment. Anti-CCP and RA factor were done to confirm diagnosis of rheumatoid arthritis. EULAR criteria was used to diagnose rheumatoid arthritis and patients with EULAR score of > 6 were