INTRODUCTION The utilization and ubiquity of rare earth metal nanoparticles (NPs) have grown in recent years. A substance that is utilized and produced in the form of rods, sheets, nanotubes, and NPs for its electrochemical uses. Researchers have developed organic nanomaterials such as liposomes, dendrites, albumin-coated NPs, polymeric and lipid NPs. Metallic NPs are made of various metals, magnetic materials, metal oxides, and quantum dots. 1 The characteristics of yttrium oxide (Y 2 O 3 ), a kind of important rare earth element, as an inorganic NP are reviewed in this paper. According to a recent geological assessment of the United States, 3 yttrium is employed in ceramics, metallurgy, and phosphors and has an estimated rare earth element proportion of 0.12%. In 2018, China produced the majority of the world’s yttrium oxide, which was thought to be 7000 tons. Australia, Canada, China, and India are the top four countries that produce yttrium reserves. As a component of salts, liquid reactive molten alloys, and uranium-resistant refractory ceramic, Y 2 O 3 is used in atomic reactors. 4,5 Metal- oxide-semiconductor devices also create a fantastic protective coating that serves as an alternative to silicon dioxide. It is frequently employed as a high-temperature resistant sealant and abrasive in the ceramic sector. It also serves as a paint for jet engines and an oxygen sensor in autos. It won’t rust as a result of the cutting tools. 6,7 It is the best alloy, a grain refning additive, an anti-oxidizer, and a high-temperature conductor in metallurgy. Yttrium derivatives are used in the electrical areas of microwave surveillance, internet technology, temperature monitoring, optoelectronic devices, photoreactions, and fuorescence spectroscopy. The diferent electrical properties, chemical stability, and enhanced hardness of Y 2 O 3 NPs have all been documented in the literature. They added that it can be used in solar energy systems, lithium-ion batteries, and parts for rare-earth-doped lasers. Researchers have found that acetaminophen may be detected with good electrocatalytic activity using a mixture of carbon nanotubes (CNTs) and Y 2 O 3 . Y 2 O 3 NPs, which are rare earth materials, have all the necessary characteristics for phototherapy, 8 biological imaging, 9 luminescence, 10 and nuclear power systems. 11 A surprisingly high refractive index, a wide band gap (5.8 eV), a strong dielectric constant, and a high thermal stability area are among these characteristics. 12 Y 2 O 3 Nps were produced using a thermal process, and they had diameters and edge lengths on the order of micrometers. 13 ABSTRACT Corrosion processes cause considerable losses in industry and the economy. Corrosion inhibitors have been used in both inorganic and organic forms for a long time. Nanomaterials are more efective at preventing corrosion than traditional materials because they have a higher surface-to-volume ratio. Metal oxide nanoparticles (NP) are also novel in a variety of technological applications due to their distinct physical and chemical properties. Due to their higher dielectric constant and thermal stability, yttrium oxide (Y 2 O 3 ) nanoparticles (NPs) are well known for technical applications. It is frequently utilized in electrochemical applications, photodynamic treatment, and other sectors as a host material for a range of rare-earth alloying elements. As a polarizer, phosphor, biosensor, laser host material, and for bioimaging, Y 2 O 3 NPs has also been employed. Anti-corrosion characteristics of yttrium oxide nanoparticles are appealing regarding the formation of a smooth adsorbed layer on metal surfaces or alloys. This review focuses on Y 2 O 3 NPs promising usage and developments in corrosion-inhibiting applications. The processes of green, chemical, hydrothermal and sol-gel nanoparticle synthesis are discussed. Keywords: Anti-corrosion applications, Green synthesis, Rare earth metals, Yttrium oxide. International Journal of Drug Delivery Technology (2022); DOI: 10.25258/ijddt.12.4.72 How to cite this article: Hassin MJ, Salman TA. Review of Green Synthesis and Anticorrosion Applications for Yttrium Oxide Nanoparticles. International Journal of Drug Delivery Technology. 2022;12(4):1911-1915. Source of support: Nil. Confict of interest: None Review of Green Synthesis and Anticorrosion Applications for Yttrium Oxide Nanoparticles Maha J. Hassin, Taghried. A. Salman* Department of Chemistry, College of Science, Al-Nahrain University ,Jadriah, Baghdad, Iraq Received: 22 nd August, 2022; Revised: 03 rd September, 2022; Accepted: 11 st November, 2022; Available Online: 25 th December, 2022 REVIEW ARTICLE *Author for Correspondence: dr.tag_s@yahoo.com