Uncorrected Proof Middle East J Rehabil Health Stud. In Press(In Press):e100235. Published online 2020 April 12. doi: 10.5812/mejrh.100235. Research Article Effect of Ankle Kinesio Taping on Unaffected Foot in Stand-to-Sit Position in Patients with Chronic Stroke Majid Menhaj 1 , Roghayeh Mohammadi 2, * , Abbas Ziari 3 and Kazem Malmir 4 1 Student Research Committe, Semnan University of Medical Sciences, Semnan, Iran 2 Neuromuscular Rehabilitation Research Center, Semnan University of Medical Sciences, Semnan, Iran 3 Social Determinants of Health Research Center, Semnan University of Medical Sciences, Semnan, Iran 4 Rehabilitation Faculty, Tehran University of Medical Sciences, Tehran, Iran * Corresponding author: Neuromuscular Rehabilitation Research Center, Semnan University of Medical Sciences, Semnan, Iran. Email: mohamadipt@gmail.com Received 2019 December 16; Revised 2020 February 29; Accepted 2020 March 04. Abstract Objectives: The current study aimed at investigating the effect of applied Kinesio tape on the affected ankle on the amount of exerting force by the non-affected foot in patients with chronic stroke during the stand to sit task. Methods: The current quasi-experimental clinical trial was conducted on 26 patients with chronic stroke. The stand-to-sit task was performed in three positions (symmetric foot placement, and placing the unaffected foot ahead of the affected foot and the unaffected foot behind the affected one), and the vertical axis of the ground reaction force was recorded instantly by a force plate at three time points of 2, 5, and 8 seconds of the stand-to-sit task. Then, Appropriate taping was applied on subjects‘ affected ankles and all measurements were repeated. Results: At the time points of 2 and 5 seconds, the main effect of foot positions was significant (P = 0.002 and P < 0.0001, respec- tively); when the tested foot was placed behind, the main effect was significantly different from those of other positions (P = 0.018). However, the main and interactive effect of the tape was not significant (P > 0.05). At the second eight, no significant change was observed (P > 0.05). Conclusions: The current study findings showed that placing the unaffected foot behind the affected one led to more force and there was no significant difference between the forces with and without using the tape. Keywords: Kinesio Tape, Chronic Stroke, Stand-to-Sit 1. Background Stroke is one of the leading causes of mortality in devel- oped countries and disability in industrialized regions (1). Following the stroke, patients lose their balance, which is associated with asymmetry in weight distribution, postu- ral stability, and narrower stability range. Inadequate bal- ance leads to a reduction in the independent function of individuals and increased risk of falling (2). Change from sitting to standing position and vice versa is one of the es- sential activities in daily life (3), which is the basis of mov- ing from bed to chair and chair to toilette (4); it is a fun- damental requirement for walking and mobility and re- quires a reasonable functional ability of lower limbs and postural control (5). Previous studies showed that the change of foot po- sitions majorly affects the force of foot in patients with stroke during sit-to-stand and stand-to-sit tasks (6-9). The important finding is that positioning the affected foot be- hind improves the symmetry of vertical reaction force or both-side extension torque. Liu et al. (10), found that posi- tioning the affected foot behind is effective in controlling balance in such patients. Most studies evaluate the sit-to- stand properties of patients with stroke (6, 7, 11-13), but few studies are conducted on stand-to-sit positioning and the force applied on unaffected foot. Many studies found the role of ankle-foot orthosis (AFO) in the functional and pos- tural stability of patients with stroke (14-17). In other stud- ies, ankle-foot kinesio tape was used to improve stability during standing (18-20). Studies showed that ankle-foot kinesio tape through correct positioning of the foot resulted from the increase in sensory input can effectively improve the function, in- crease the range of motion (21, 22), and cause increased sta- bility (20). 2. Objectives Besides, using the tape is easy and cost-effective and the results are achieved soon. Therefore, the current study Copyright © 2020, Middle East Journal of Rehabilitation and Health Studies. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.