DOI: 10.14260/jemds/2014/3759 CASE REPORT J of Evolution of Med and Dent Sci/ eISSN- 2278-4802, pISSN- 2278-4748/ Vol. 3/ Issue 58/Nov 03, 2014 Page 13215 A VERY RARE CASE OF SKIN ADNEXAL NEOPLASM: HIDRADENOMA Sunil Kumar 1 , Basavaraj Badadal 2 , M. B. Patil 3 , Ramakanth Baloorkar 4 , Dayanand Biradar 5 HOW TO CITE THIS ARTICLE: Sunil Kumar, Basavaraj Badadal, M. B. Patil, Ramakanth Baloorkar, Dayanand Biradar. “A Very Rare Case of Skin Adnexal Neoplasm: Hidradenoma”. Journal of Evolution of Medical and Dental Sciences 2014; Vol. 3, Issue 58, November 03; Page: 13215-13220, DOI: 10.14260/jemds/2014/3759 ABSTRACT: DEFINITION: Hidradenoma is a form of benign adnexal neoplasm that is a close relative of poroma, but is characterized by cells with ample cytoplasm 1-4 . Here we present a very rare and interesting case of a 35 year old female patient who presented to surgical opd with the complaints of swelling in front of the middle of the neck since two years. Swelling was not associated with any other complaints like pain, difficulty in swallowing, difficulty in speaking and difficulty in pronunciation of words. With adequate pre-operative preparation and normal routine blood investigations, patient was posted for surgery under monitored anesthesia care {ie.MAC}. A wide local excision was performed and specimen was sent for histopathological examination. HPR revealed an eccrine clear cell hidradenoma of neck. On follow-up for 2 year there has been no recurrence. KEYWORDS: INTRODUCTION: Hidradenoma is a benign tumor, which usually presents as a solitary, skin‐colored lesion and occurs more commonly in females 5 . Hidradenoma may have variable histomorphological patterns reflected by the various terms used to describe this entity: nodular hidradenoma, eccrine acrospiroma, solid‐cystic hidradenoma, clear cell hidradenoma, and clear cell acrospiroma. In fact, some tumours have epidermal attachment, and occasionally may also have features overlapping with those of typical poromas. Clear cell change and/or squamous metaplasia may be prominent. However, squamoid change does not seem to denote a worse prognosis. The lesion is also characterized by its pushy, but well‐circumscribed, peripheral border. Nodular hidradenoma should be fully excised, as malignant transformation may be present in other areas of the lesion. Furthermore, hidradenoma has a recurrence rate of approximately 12% if not fully excised, especially in lesions with irregular peripheral margins. 6 CASE REPORT: A 35 year old female patient presented to our surgical opd with complaints of swelling in front of the middle of the neck since two years. Swelling was not associated with any other complaints like pain, difficulty in swallowing, difficulty in speaking and difficulty in pronunciation of words. On examination there was a solitary swelling horizontally measuring 3cm*2cm, swelling was horizontally oval in shape. Skin over the swelling was normal ie.no dilated or engorged veins & there were no scar marks over the swelling. Surrounding skin was hyper pigmented but non-erythematous. Swelling was having well-defined edges & margins, surface was smooth. Swelling was firm to hard in consistency. Swelling was not moving with deglutition. Swelling was freely mobile both in cranio-caudal and horizontal directions. With adequate pre-operative preparation and normal routine blood investigations, patient was posted for surgery under monitored anesthesia care {i.e. MAC}. A wide local excision was performed and specimen was sent for