International Journal of Research in Medical Sciences | November 2022 | Vol 10 | Issue 11 Page 2560 International Journal of Research in Medical Sciences Vishwakarma S et al. Int J Res Med Sci. 2022 Nov;10(11):2560-2566 www.msjonline.org pISSN 2320-6071 | eISSN 2320-6012 Original Research Article Impact of premenstrual syndrome and premenstrual dysphoric disorder on adolescent and young women’s quality of life in northern India Swati Vishwakarma 1 , Sujata Deo 1 *, Pooja Mahaur 2 , S. P. Jaiswar 1 , Monica Agrawal 1 INTRODUCTION PMS is a recurrent recurrence of painful physical and emotional symptoms during the luteal phase of the menstrual cycle and the first few days (1-3 days) of the following follicular phase. Feeling overwhelmed, food cravings, insomnia or hypersomnia, headache, pelvic pain and discomfort, breast tenderness, joint pain, bloating are the most common and distressing somatic symptom whereas irritability, anxiety, depression, mood swings, hostility poor concentration, confusion, social withdrawal and interpersonal conflicts are the affective symptoms. 1,2 The onset of these symptoms is noticeable as early as adolescence and worsens as one get older or reaches maturity. Up to 40% of women in reproductive age suffer some type of PMS, although only 3-9% have severe phycological symptom- PMDD (premenstrual dysphoric disorder). PMDD is a severe and debilitating type of premenstrual syndromes (PMS) which is caused by fluctuating levels of sex steroids throughout an ovulatory menstrual cycle. 3 1 Department of Obstetrics and Gynecology, 2 Department of Psychiatry, King George Medical University, Lucknow, Uttar Pradesh, India Received: 09 September 2022 Revised: 04 October 2022 Accepted: 10 October 2022 *Correspondence: Dr. Sujata Deo, E-mail: drsujata.2008@rediffmail.com, sujata@kgmcindia.edu Copyright: © the author(s), publisher and licensee Medip Academy. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ABSTRACT Background: Our aim was to study the effect of PMS and PMDD on quality of life in adolescent and young women. Methods: This was a cross-sectional questionnaire based study was conducted from 2019 to 2020 in Department of Obstetrics and Gynecology, King Georges Medical University, Lucknow. After getting informed consent 358 female participant was enrolment. All participants were screened first according to PMS ACOG guideline then further DSM IV based premenstrual symptom screening tool (PSST) was applied by enquiring detail about last 3 menstrual cycles. The subjects which are diagnosed were given WHO-QOL-BREF scale. Results: The work efficiency or productivity, relationship with co-workers, relationship with your family, social life activities and home responsibilities were 27.63%, 26.31%, 22.36%, 15.78% and 15.13% in no/mild PMS, 94.73%, 86.84%, 73.68%, 60.52% and 42.10% in moderate to severe PMS and 100.00%, 85.71%, 57.14%, 42.85%, and 2.85% PMDD. The mean percentages of physical health domain were 64.43±8.29, 58.47±6.91, and 52.86±6.20; psychological health domain was 66.39±9.39, 62.47±7.73 and 56.29±4.64; social relationship domain was 62.29±12.45, 60.61±11.67 and 56.00±5.32 and environmental health domain was 64.52±9.64, 61.13±9.39 and 58.86±3.72 in no/mild PMS, moderate to severe PMS and PMDD participants group, respectively. Conclusions: The changes of physical health domain, psychological health domain were significantly negative correlated with moderate to severe PMS that means participant with moderate and severe PMS have poor quality of physical and psychological health whereas, social relationship domain and environmental health domain were also negative correlated but not significantly associated with moderate to severe PMS. Keywords: Adolescent, Depression, Premenstrual dysphoric disorder, Premenstrual syndrome, Quality of life DOI: https://dx.doi.org/10.18203/2320-6012.ijrms20222858