_____________________________________________________________________________________________________ *Corresponding author: E-mail: dr.israel.jeremiah@gmail.com; International STD Research & Reviews 4(3): 1-9, 2016; Article no.ISRR.27420 ISSN: 2347-5196, NLM ID: 101666147 SCIENCEDOMAIN international www.sciencedomain.org Chlamydia trachomatis Infection: Serological Evidence in Women with Ectopic Pregnancy in Port Harcourt Vitalis Chinonye Ibe 1 , Israel Jeremiah 2* and Eugene Ikeanyi 2 1 Department of Obstetrics and Gynaecology, University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria. 2 Department of Obstetrics and Gynaecology, College of Health Sciences, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria. Authors’ contributions This work was carried out in collaboration between all authors. Author VCI designed the study, wrote the protocol and wrote the first draft of the manuscript. Authors IJ and EI performed the statistical analysis and managed the analyses of the study. Author IJ managed the literature searches. All authors read and approved the final manuscript. Article Information DOI: 10.9734/ISRR/2016/27420 Editor(s): (1) Jose Eduardo Serrao, Department of General Biology, Federal University of Viçosa, Brazil. Reviewers: (1) Suncanica Ljubin-Sternak, University of Zagreb, Croatia. (2) Edith Angel-Muller, Universidad Nacional de Colombia, Colombia. (3) Guadalupe García-Elorriaga, Mexican Social Security Institute, Mexico. Complete Peer review History: http://www.sciencedomain.org/review-history/16886 Received 31 st May 2016 Accepted 18 th October 2016 Published 11 th November 2016 ABSTRACT Background: Genital chlamydial infection is the most commonly reported bacterial sexually transmitted disease worldwide. It poses a public health problem of epidemic proportions. Untreated or poorly treated cases result in endosalpingeal damage and destruction of tubular architecture with multiple sequelae including tubal infertility and ectopic pregnancy. Aims: To determine serological evidence of prior chlamydial infection in patients with ectopic pregnancy and to investigate associations between prior Chlamydia infection, its risk factors and ectopic pregnancy in Port Harcourt. Materials and Methods: This was a case-control study carried out at the University of Port Harcourt Teaching Hospital, involving 64 women treated for ectopic pregnancy who served as subjects and the 64 women with normal intrauterine pregnancies drawn from the antenatal clinic Original Research Article