Journal of Animal Research: v.10 n.4, p. 585-591. August 2020 DOI: 10.30954/2277-940X.04.2020.17 How to cite this article: Rath, P.K., Panda, S.K., Mishra, B.P., Karna, D.K. Sahoo, G.R., Mishra, U. and Patra, R.C. (2020). Clinico-pathological evaluation of PPR in a flock of Ganjam sheep and goat in Odisha. J. Anim. Res., 10(4): 585-591. Source of Support: None; Conflict of Interest: None Clinico-pathological Evaluation of PPR in a Flock of Ganjam Sheep and Goat in Odisha Prasana Kumar Rath 1* , Susen Kumar Panda 1 , Bidyut Prava Mishra 2 , Dillip Kumar Karna 3 , Gyana Ranjan Sahoo 4 , Umakanta Mishra 5 and Ramesh Chandra Patra 6 1 Department of Veterinary Pathology, College of Veterinary Science & Animal Husbandry, Odisha University of Agriculture & Technology, Bhubaneswar, Odisha, INDIA 2 Department of Livestock Products Technology, College of Veterinary Science & Animal Husbandry, Odisha University of Agriculture & Technology, Bhubaneswar, Odisha, INDIA 3 OIC, AICRP on Goat Improvement, College of Veterinary Science & Animal Husbandry, Odisha University of Agriculture & Technology, Bhubaneswar, Odisha, INDIA 4 Department of Veterinary Biochemistry, College of Veterinary Science & Animal Husbandry, Odisha University of Agriculture & Technology, Bhubaneswar, Odisha, INDIA 5 Department of Veterinary Anatomy & Histology, College of Veterinary Science & Animal Husbandry, Odisha University of Agriculture & Technology, Bhubaneswar, Odisha, INDIA 6 Department of Veterinary Clinical Medicine, College of Veterinary Science & Animal Husbandry, Odisha University of Agriculture & Technology, Bhubaneswar, Odisha, INDIA *Corresponding author: PK Rath; E-mail: drpkrath78@gmail.com Received: 10 May, 2020 Revised: 16 June, 2020 Accepted: 27 June, 2020 ABSTRACT Present study was aimed to investigate the mortality among a fock of Ganjam sheep and goat during December, 2016 in Odisha. These breed of small ruminant mostly reared in nomadic pattern by certain “Gola” community with native tract mostly in south-eastern and eastern-ghat of agroclimatic zones in Odisha with hot and humid climate. Clinical signs and gross lesions as observed among the animals were indicative of Peste des petits ruminants (PPR). There was nearly 90% morbidity and 42.22% mortality. Higher mortality was recorded among the weaners (~ 63%) followed by kids (~ 42%). Blood examination revealed anemia with signifcantly (p ≤0.05) decrease in total erythrocyte counts (TEC) and packed cell volume (PCV) through t-test. Affected animals showed leucocytosis with nutrophillia and lymphopaenia. Statistically signifcant (p ≤0.05) alterations in various serum biochemical parameters were evident in morbid animals. At necropsy, typical lesions were erosive as well as hemorrhagic lesions in buccal mucosa, abomasums and intestine along with fbrinous bronchopneumonia. Histopathological changes were mostly infltrations of infammatory cells, syncytia and presence of intranuclear and /or intracytoplasmic eosinophillic inclusions in epithelial cells, alveolar macrophages, lungs and hepatocytes. HIGHLIGHTS m Pathology of PPR in Ganjam breeds of sheep and goats in Odisha. m Hot humid climate, nomadic pattern of rearing of Ganjam sheep and goats by “Gola community” were incrementing factors for PPR. Keywords: Ganjam goat, Ganjam sheep, mortality, pathology, PPR Peste des petits ruminants (PPR) is an important emerging disease among small ruminants causing large scale mortality and morbidity among small ruminants results a huge economic loss. The causative agent of this disease is