Background: Phosphorus (P) is an important electrolyte that plays a significant in different physiological processes espe- cially muscle contraction and adenosine triphosphate high energy bonds. Low phosphorus level in blood may increase the exacerbation of chronic obstructive pulmonary disease, need, and duration of mechanical ventilation. Objective: To examine the prognostic effects of hypophosphate- mia in COPD patients and evaluate the correlation between phosphorus levels and severity of attacks, need for mechanical ventilation, duration of The ICU stays and mortality. Methods: This study was performed on 72 patients with acute exacerbation of COPD admitted in chest department and respi- ratory ICU in Ain Shams University Hospital in the period between June 2019 & March 2020. Results: The study showed Low blood phosphorus levels con- tribute to an increase in: COPD flare-up with high statistically on, dura- intensive statisti- & of disor- crucial rate . Sulphate after Surgical Repair of Moderate Size Umbilical Hernia Mohamed Hossam El Din Hamdy Shokeir, Ahmed Mohamed El Sayed El Henawy, Simon Halim Armanios, Shaimaa Mansour Abd Elkader Morgan Department of Anesthesia, Intensive Care and Pain manage- ment Ain Shams University Corresponding author: Shaimaa Mansour Abd Elkader Morgan, Mobile: 01026416423; Email:drshimaamansour@gmail.com Background: The transversus abdominis plane (TAP) block is a known approach for blocking the abdominal wall neural affer- ents via the bilateral lumbar triangles of Petit. Different adju- vants have been used to intensify the quality and the duration of local anesthetics. Aim of the Work: The aim of this study is to detect the efficacy and safety of magnesium sulphate as an adjuvant to the analge- sia offered by local anesthetic in ultrasound guided TAP block in patients undergoing surgical repair of moderate sized umilical hernia under general anathesia. As regard postoperative pain and opioid consumption using Visual Analogue scale VAS. Patients and Methods: the study was carried out on 40 patients who was undergo surgical hernial repair, after ethical approval of Ain Shams University Hospital and informed consent from patients ,patients assigned in two group ,each group include 20 patients, Group 1: receive TAP block with Bupivacaine 0.25% 20 ml per side. Group 2: receive TAP block with Bupivacaine 0.25% 18 mLþ2 ml magnesium sulphate. Results: By the end of our study we found that VAS pain score was less in group II than in group I at 0,1,2 and 24 hours postoperatively and most significant at 4,6 and 12 hours the VAS score less in group II than group I (p value <0.05).And the mean time for first rescue analgesic dose was delayed in group II (872.876 (p value < sounded prolong rescue Key magnes Effect of Growth Hormone on Outcome of Pediatric Burn Patients Gihan Seif El Nasr Mohamed, Salwa Omar ElKhattab Amin, Mohamed Mohamed Kamal, Sherif Hany Adly Loka Anesthesia, ICU & Pain Management Department, Faculty of Medicine, Ain Shams University Background: A burn is a thermal injury caused by biological, chemical, electrical and physical agents with local and systemic repercussions. There are several ways of classifying burns: Classification by mechanism or cause, Classification by the degree and depth of a burn, Classification by extent of burn the extent of burn. Objectives: The objective of this study was to determine the safety and efficacy of using recombinant human growth hor- mone (rhGH) in the treatment of pediatric burn victims and their ICU length of stay, mortality and morbidity. Patients and Methods: This study was an Interventional randomized controlled Double Blind Study in which Patients subdivided randomly into 2 groups: Group A received somato- tropine hormone after their 3 days of resuscitation besides their conventional treatment during their stay in the Burn ICU. Group B received the conventional treatment only in the Burn ICU. Results: The comparison between the GH group and the control group showed that the mean ICU stay in days in GH group was 10.88 while in the control group 13.59 with P value 0.018 as a sig- nificant result as the GH group showed a less ICU stay time than the control group with approximately 20%. Mortality in the GH group was 6.2% from the total number of the group while in control group 18.8% from the total number of the group with P value 0.033 as a significant result yet the mortality may also depend on other factors as the degree of burn and the area of burn and the associated events like inhalational injury or delay post burn or any other co-morbidity. Morbidity results seen was 0% in control group and 4.7% in GH group with P value 0.080 as a non-significant result, morbidity was in the form of hyperglycemia. Conclusion: The use of recombinant Growth hormone with a dose of 0.2 mg/Kg SQ 2 days per week with 3 days time interval in pediatric burn patients after their primary resuscitation from the burn injury, shows a marvelous improvement concerning the ICU stay time as the patient received the growth hormone showed an approximately 20% time less ICU stay than the con- trol group this may be accounted for the faster wound healing and readiness for grafting and even faster graft healing, also a decreased mortality in a significant way, although mortality may depend on many factors in burn patients like degree of QJM: An International Journal of Medicine, 2021, Vol. 114, Suppl. 1 | i43 Downloaded from https://academic.oup.com/qjmed/article/114/Supplement_1/hcab086.105/6379584 by guest on 06 May 2023