462 Oral communications
regression, three stable, three moderate), 16 PG (four regression,
four stable, four moderate), 17 LAVVR (six regression, seven stable,
four moderate). Image quality of micro-TEE was scored 1 for 2D and
2 for Doppler. In three patients on circulatory assistance, micro-TEE
could be performed in PICU with good tolerance and acceptable
quality.
Conclusions.— TEE is a tool to evaluate hemodynamic significance
of post-operative residual lesions. This new microprobe offers the
possibility to perform TEE in small infants in the OR and in unstable
patients with poor imaging TTE in PICU.
http://dx.doi.org/10.1016/j.acvd.2013.06.006
03
Coronary artery compression during transcatheter
right-ventricular outflow tract treatment:
Incidence, diagnosis and outcome
Alain Fraisse
a,e
, Anass Assaidi
a,e
, Sophie Malekzadeh-Milani
b,c,e
,
Mehul Patel
b,c,e
, Damien Bonnet
b,d,e
, Younes Boudjemline
b,c,d,e
a
Cardiologie Pédiatrique, Hôpital de la Timone-Enfants, 264, rue
St-Pierre, 13385 Marseille Cedex 05, France
b
Centre de Référence Malformations Cardiaques Congénitales
Complexes (M3C), Necker Hospital for Sick Children, Assistance
Publique des Hôpitaux de Paris, Pediatric Cardiology, Paris, France
c
Centre de Référence Malformations Cardiaques Congénitales
Complexes (M3C), George-Pompidou European Hospital,
Assistance Publique des Hôpitaux de Paris, Unit for Adults with
congenital heart defects, Paris, France
d
Université Paris Descartes, Sorbonne Paris Cité, Paris, France
e
Hospital Bordeaux, Unit for children and Adults with congenital
heart defects, Bordeaux, France
Background.— Coronary compression (CC) may occur during per-
cutaneous pulmonary valve implantation (PPVI) and is potentially
life threatening when undiagnosed before right ventricular outflow
tract (RVOT) stenting. We sought to evaluate its incidence, diagnosis
and outcome.
Methods.— All consecutive patients who underwent transcatheter
RVOT treatment from May 2008 to December 2011 in two institutions
were studied. Baseline demographics, diagnosis and outcomes of CC
were reviewed with analysis of risk factors.
Results.— CC occurred in six out of 100 patients (6%) at a median
age of 24 (13 to 49) years, with RVOT conduit stenosis as the
primary lesion in all cases. The initial congenital heart disease
was pulmonary atresia-ventricular septal defect (n = 3), complex
transposition of the great arteries (n = 2) and critical aortic steno-
sis status-post Ross operation (n = 1). The RVOT initial median
conduit diameter at surgical implantation was 23 (17 to 24) mm
and conduit types were homograft (n = 3), bioprothesis (n = 2) and a
pericardial patch (n = 1). CC was diagnosed by coronary angiogram
during balloon dilation of the RVOT in all cases whereas it was
suspected on pre-procedure computed tomography (CT-scan) in
only two cases. Compression occurred on the left anterior des-
cending coronary artery in four cases and on a right coronary
artery that arose from the proximal left anterior descending coro-
nary artery in two patients (single coronary artery). No risk factor
was found but there was a significantly higher incidence of CC
in one of the two institutions (P = 0.04). CC was well-tolerated
and resolved after the balloon was deflated in all the cases. No
patients underwent RVOT stenting or PPVI. Surgical conduit replace-
ment was electively performed in three patients. Two patients with
moderate residual RVOT stenosis are followed. One patient with
encephalopathy and respiratory insufficiency died 9 months after
catheterization.
Conclusions.— CC is efficiently diagnosed by coronary angiogram
during balloon dilation in patients undergoing transcatheter
interventions on RVOT. Diagnosis by pre-procedure CT-scan is
not accurate. No specific risk factors exist. Surgical conduit
replacement is indicated when balloon dilation fails to improve the
RVOT obstruction.
http://dx.doi.org/10.1016/j.acvd.2013.06.007
04
The influence of closure of patent ductus
arteriosus on left and right ventricular size and
function
Laurianne Le Gloan
a
, Jean-Benoît Thambo
b
, Julie Chabaneix
b
,
Jean-Marc Langlard
a
, Véronique Gournay
a
, Cécile Pascal
a
,
Bénédicte Romefort
a
, Quentin Hauet
a
, Nadir Benbrik
a
,
Olivier Baron
a
, Patrice Guérin
a
a
Institut du thorax, University hospital of Nantes, Nantes, France
b
Service des cardiopathies congénitales de l’enfant et de
l’adulte, University hospital of Bordeaux, Bordeaux-Pessac,
France
Background.— Patent ductus arteriosus is responsible for left ven-
tricular diastolic and right ventricular systolic overload. Little is
known about hemodynamic changes after percutaneous and surgical
closure.
Methods.— We conducted a bicentric prospective study, of chil-
dren, with patent ductus arteriosus, evaluating the evolution
of systolic and diastolic ventricular function before, 1 day and
1 month after successful closure, by means of transthoracic
echocardiography.
Results.— Thirty-three children, age 3 months to 14.5 years, under-
went successful closure of their patent ductus arteriosus, 32
percutaneously and one surgically. All patent ductus arteriosus
were closed for hemodynamic reasons, with a mean diame-
ter of 3.6 ± 0.9 mm. There was a significant increase in systolic
(100.6 ± 15.1 versus 95.4 ± 15.3 mmHg, P < 0.05) and diastolic
(53.2 ± 17.1 versus 47.8 ± 17.2 mmHg, P < 0.05) blood pressures,
immediately after the suppression of the shunt. Left ventricu-
lar fractional shortening and end-diastolic volumes index were
significantly lower the day after closure (respectively 34.7 ± 5.5
versus 37.8 ± 4.7% and 47 ± 16.2 versus 54.6 ± 20.1 mL/m
2
) and
remained low compared to the preclosure state at follow-up
(respectively 33.8 ± 5.4 versus 37.8 ± 4.7% and 47 ± 12.7 versus
54.6 ± 20.1 mL/m
2
). A non-significant decrease in left ventricular
filling pressures was observed. Right ventricular systolic parameters
(TAPSE) were significantly lower 1 month after closure (19.3 ± 2.9
versus 21.4 ± 4.4 mm, P < 0.05).
Conclusion.— Changes in left ventricular volume and function and
in right ventricular function occur immediately after patent duc-
tus arteriosus closure, and remain at 1 month of follow-up. Further
studies are warranted to increase the number of patients and the
duration of follow-up.
http://dx.doi.org/10.1016/j.acvd.2013.06.008
05
A 10-year study of planned delivery of foetuses
with prenatally diagnosed congenital heart disease
in a single institution
M. Bensemlali
a,b
, F. Raimondi
a,b
, L. Fermont
a,b
, J. Le Bidois
a,b
,
L. Salomon
a,b
, D. Bonnet
a,b
a
M3C-Necker Enfants maladies, AP—HP, Université Paris
Descartes, Sorbonne Paris Cité, Paris, France
b
Maternité, Necker-Enfants maladies, AP—HP, Université Paris
Descartes, Sorbonne Paris Cité, Paris, France
Objectives.— To describe the aims and rationale for planned deliv-
ery in a tertiary referral centre for foetuses with prenatal diagnosis
of congenital heart disease.
Methods and results.— Two thousand one hundred and thirty con-
secutive foetuses with congenital heart disease diagnosed from
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