Open Journal of Obstetrics and Gynecology, 2019, 9, 1151-1160 http://www.scirp.org/journal/ojog ISSN Online: 2160-8806 ISSN Print: 2160-8792 DOI: 10.4236/ojog.2019.98111 Aug. 15, 2019 1151 Open Journal of Obstetrics and Gynecology Successful Management of Takayasu’s Arteritis with Pulmonary Hypertension in Pregnancy: A Rare Case Wiryawan Permadi, Dani Setiawan, Muhammad Alamsyah Aziz * , Yanuarman, Anita D. Anwar, Firman Fuad Wirakusumah Obstetrics and Gynecology Department, Faculty of Medicine, Padjadjaran University, Hasan Sadikin Hospital, Bandung, Indonesia Abstract Introduction: Takayasu’s arteritis (TA) is a rare systemic, chronic inflam- matory, progressive, idiopathic disease of aorta and its main branches. Ta- kayasu’s arteritis causes narrowing, occlusion and aneurysm of arteries. The etiology of TA is still unknown. It may be autoimmune or genetic in origin or infective diseases. It is commonly found in Asia and oriental countries. Worldwide annual incidence is 1.2 - 2.6 cases/million. Women are affected in 80% - 90% of cases with age of onset below 40 years. TA does not worsen or improve with pregnancy but has adverse effect on pregnancy in the form of abortion, Intrauterine fetal death, superimposed preeclampsia, Intrauterine growth restriction, abruption and congestive heart failure. Because the disease is common in women of childbearing age, management of pregnancy in these patients becomes important; however optimal management for pregnant pa- tients with this disease has not yet been established. Due to the manifold car- diovascular complications that can occur in the course of the disease, man- agement of pregnancies in TA patients is a challenge for the clinician. An in- terdisciplinary collaboration of obstetrician, rheumatologist, cardiologist and anaesthetist is necessary to improve maternal and fetal prognosis. This was the first reported case of TA in pregnancy in Hasan Sadikin Hospital with superimposed preeclampsia and pulmonary hypertension. Materials and Methods: The patient, G1P0A0 was diagnosed as TA since one year ago, and when the patient was pregnant, the patient routinely came to obstetric and rheumatology clinics. Angiographic examination showed dilatation of aorta ascendant, narrowing of aorta descendent at 8 thoracal vertebrae, and arcus aorta, abdominal aorta and the branches were without abnormalities that lead to type IIb TA. On physical examination blood pressure was 200/100 mmHg How to cite this paper: Permadi, W., Setiawan, D., Alamsyah Aziz, M., Yanuar- man, Anwar, A.D. and Wirakusumah, F.F. (2019) Successful Management of Takaya- su’s Arteritis with Pulmonary Hypertension in Pregnancy: A Rare Case. Open Journal of Obstetrics and Gynecology, 9, 1151-1160. https://doi.org/10.4236/ojog.2019.98111 Received: June 3, 2019 Accepted: August 12, 2019 Published: August 15, 2019 Copyright © 2019 by author(s) and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Open Access