_____________________________________________________________________________________________________ *Corresponding author: Email: s_elbadrawy@mans.edu.eg & m_s_elbadrawy@yahoo.com; Eur. J. Nutr. Food. Saf., vol. 15, no. 5, pp. 6-19, 2023 European Journal of Nutrition & Food Safety Volume 15, Issue 5, Page 6-19, 2023; Article no.EJNFS.99074 ISSN: 2347-5641 Effect of Hayani Date (Phoenix dactylifera L) Peels on Blood Sugar, Blood Lipids, Liver and Kidney Functions, and Inflammation in Diabetic Rats Elsayed Elbadrawy a* , Ashraf Elzainy a , Hala Elkewawy a and Nagia Elsaid a a Home Economics Department (Nutrition and Food Science), Faculty of Specific Education, Mansoura University, Mansoura, Egypt. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/EJNFS/2023/v15i51308 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/99074 Received: 18/02/2023 Accepted: 20/04/2023 Published: 21/04/2023 ABSTRACT This study aimed to investigate the effect of Hayani date peel powder and its methanolic extract on glycemia and lipidemia in streptozotocin-induced diabetic rats as well as their effects on kidney and liver functions in addition to their anti-inflammatory activity. Twenty-four rats were used in this study, six of them served as normal control (group 1) which continued feeding on the basal diet, while the remaining 18 rats were injected with streptozotocin (50mg/kg) to induce diabetes. The diabetic rats were divided into three groups (6 rats each), one of them feeding on the basal diet only which acted as diabetic control (group 2), another group fed on the basal diet and treated Original Research Article