_____________________________________________________________________________________________________ *Corresponding author: E-mail: badarali@live.com; Journal of Pharmaceutical Research International 33(46A): 538-549, 2021; Article no.JPRI.75623 ISSN: 2456-9119 (Past name: British Journal of Pharmaceutical Research, Past ISSN: 2231-2919, NLM ID: 101631759) FEM Based Elasto-Electric Analysis of Elastomers for Pharmaceutical Applications Rumesa Nazeer 1 , Mehwish Afridi 1 , Marvi 2 , Muhammad Umair Alam 3 , Badar Ali 3* , Sana Afzal Alvi 4 and Kashif Iqbal 1 1 Department of Pharmacy, University of Lahore, Islamabad, Pakistan. 2 Department of Pharmacology, University of Balochistan, Quetta, Pakistan. 3 Department of Electrical Engineering, Sir-Syed CASE – IT, Islamabad, Pakistan. 4 AFIRI, MH, Rawalpindi, Pakistan. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JPRI/2021/v33i46A32897 Editor(s): (1) Dr. S. Prabhu, Sri Venkateswara College of Engineering, India. Reviewers: (1) Azmah Hanim Binti Mohamed Ariff, Universiti Putra Malaysia, Malaysia. (2) Ali Fadhil Naser, Al-Furat Al-Awsat Technical University, Iraq. Complete Peer review History: https://www.sdiarticle4.com/review-history/75623 Received 10 August 2021 Accepted 13 October 2021 Published 16 October 2021 ABSTRACT Elastomer materials are very important due to weak intermolecular forces and very low Young's modulus and have high failure strain. Due to these properties, they are used in a large number of applications especially in pharmaceutical industry and medical / surgical equipment etc. Electrostatic discharge on such material is a potential hazard for the operator who is dealing with elastomers. In the research presented here, a detailed analysis on the elasto-electric analysis of 03x elastomers is analyzed in detail by using Finite Element Method (FEM). A CAD model is generated in accordance with an early research on elasto-electric study of Silicon material. Subsequently FEM based analysis is carried out to study vital electrostatics properties like Surface deformation and surface potential distribution developed on the application of external forces on 03x types of elastomers i.e. Silicon Rubber, Nitrile (NBR) and Poly Vinyl Chloride (PVC). The whole study is carried out in COMSOL multi-physics software. Analysis showed that the electric field developed on the surface of the elastomer is dependent on the deformation on non-linear nature and depends upon the material properties. FEM based results show that Silicon Rubber develops maximum deformation and electric potential of three chosen materials up to 50mm and 3150V respectively. Based on the conducted analysis, Silicon Rubber is widely recommended for its utilization in Pharmaceutical applications requiring electrostatics. Original Research Article