Accepted Article This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/imb.12559 This article is protected by copyright. All rights reserved. PROF. FEDERICO FORNERIS (Orcid ID : 0000-0002-7818-1804) Article type : Original Article Structural and biochemical evaluation of Ceratitis capitata OBP22 affinity for odorants involved in inter-sex communication Marco Falchetto a,I *, Giuseppe Ciossani a,II, *, Francesca Scolari a , Alessandro Di Cosimo a , Simone Nenci a,III , Linda M. Field b , Andrea Mattevi a , Jing-Jiang Zhou b,IV , Giuliano Gasperi a , Federico Forneris a a Department of Biology and Biotechnology “L. Spallanzani”, University of Pavia, 27100 Pavia, Italy b Department of Biointeractions and Crop Protection, Rothamsted Research, Harpenden, AL5 2JQ, UK *these authors contributed equally Marco Falchetto marco.falchetto@unipv.it Giuseppe Ciossani giuseppe.ciossani@mpi-dortmund.mpg.de Francesca Scolari francesca.scolari@unipv.it Alessandro Di Cosimo alessandro.dicosimo01@universitadipavia.it Simone Nenci nenci.simone@gmail.com