The canonical poly (A) polymerase PAP1 polyadenylates non-coding RNAs and is essential for snoRNA biogenesis in Trypanosoma brucei Vaibhav Chikne, Sachin Kumar Gupta, Tirza Doniger, K. Shanmugha Rajan, Smadar Cohen-Chalamish, Hiba Waldman Ben-Asher, Liat Kolet, Nasreen Hag Yahia, Ron Unger, Elisabetta Ullu, Nikolay G. Kolev, Christian Tschudi, Shulamit Michaeli PII: S0022-2836(17)30191-2 DOI: doi:10.1016/j.jmb.2017.04.015 Reference: YJMBI 65394 To appear in: Journal of Molecular Biology Received date: 2 November 2016 Revised date: 14 April 2017 Accepted date: 23 April 2017 Please cite this article as: Chikne, V., Gupta, S.K., Doniger, T., Shanmugha Rajan, K., Cohen-Chalamish, S., Ben-Asher, H.W., Kolet, L., Yahia, N.H., Unger, R., Ullu, E., Kolev, N.G., Tschudi, C. & Michaeli, S., The canonical poly (A) polymerase PAP1 polyadenylates non-coding RNAs and is essential for snoRNA biogenesis in Trypanosoma brucei, Journal of Molecular Biology (2017), doi: 10.1016/j.jmb.2017.04.015 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.