*Correspondence to Author: João Victor de Oliveira Alves Biochemistry Department, Univer- sidade Federal de Pernambuco, Recife, Pernambuco, Brazil; How to cite this article: João Victor de Oliveira Alves, Francisco Henrique da Silva, Ma- ria Victoria dos Santos Alves Eva- risto, Janderson Weydson Lopes Menezes da Silva, Paloma Maria da Silva, Larissa Gomes de Arru- da, Irivânia Fidelis da Silva Aguiar, Saulo Almeida de Menezes, Fálba Bernadete Ramos dos Anjos, Már- cia Vanusa da Silva1.Antioxidant Activity and Hemotoxicity of Medic- inal Plant of the Caatinga Domain: Amburana Cearensis (Fabaceae) International Journal of Bioscience and Medicine, 2020; 4:13. eSciPub LLC, Houston, TX USA. Website: https://escipub.com/ João Victor de Oliveira Alves et al., IJBM, 2020; 4:13 International Journal of Bioscience and Medicine (ISSN:2575-7814) Research Article IJBM (2020) 4:13 Antioxidant Activity and Hemotoxicity of Medicinal Plant of the Caatinga Domain: Amburana Cearensis (Fabaceae) Amburana cearensis is a medicinal species popularly known as “cherry” or “aroma amburana” that has wide distribution in South America, being characteristic of Seasonal Forests. It also occurs in Semideciduous Seasonal Forest, restricted to rocky or limestone outcrops; in Submontane Deciduous SubmontanaSe- asonalForest; in Dense Ombrophilous Forest (Atlantic Forest) and even in caatinga/dry forest. Taking into account the growing interest in the search for agents that act in the face of oxidative stress, without causing toxic effects to biological systems, the present study aimed to investigate the phytochemical compo- sition and evaluate the antioxidant and hemotoxic activities in vitro of the aqueous extract obtained from the shells of Ambu- rana cearensis (EAAc). Hemaglutination wasevaluated for hu- man erythrocytes collected from people with the presence of O+ blood. In the face of the tests, Amburana cearensis presented signifcant results for antioxidant activity without causing erythro- cyte hemolysis, highlighting the importance of the species as a source of antioxidant agents, which are recognized for blocking the evolution and acting to combat symptoms triggered by dis- eases associated with oxidative stress. Keywords: Caatinga. Aqueousextract. Erythrocytes. Free radi- cals. João Victor de Oliveira Alves 1 *, Francisco Henrique da Silva 1 , Maria Victoria dos Santos Alves Evaristo 2 , Janderson Weydson Lopes Menezes da Silva 3 , Paloma Maria da Silva 1 , Larissa Gomes de Arruda 1 , Irivânia Fidelis da Silva Aguiar 1 , Saulo Almeida de Menezes 1 , Fálba Bernadete Ramos dos Anjos 4 , Márcia Vanusa da Silva 1 1 Biochemistry Department, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil; 2 Graduated in Biological Sciences, Institute of Biological Cienicas, Campus Santo Amaro, Universidade de Pernambuco; 3 Aggeu Magalhães Institute (IAM) - FIOCRUZ/PE, Brazil. 4 Department of Histology and Embryology, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil ABSTRACT Https://escipub.com/international-journal-of-bioscience-and-medicine/ 1