Pergamon
PII: S0040-4020(97)0097 3-3
Tetrahedron, Vol.53, No. 45, pp. 15459-15467,1997
© 1997Published by Elsevier Science Ltd
All rightsreserved.Printed in GreatBritain
0040-4020/97$17.00+ 0.00
Suzuki Polycondensation: On Catalyst Derived Phosphorus Incorporation and
Reproducibility of Molecular Weights
J6rg Frahn, Birol Karakaya, Andreas Sch~fer, A.-Dieter Schltiter*
Freie Universitat Berlin,Institut fllrOrganische Chemic
Takustr. 3, D-14195Berlin, Germany
Fax: 0049-(0)30838 3357,e-mail: adschlue@chemie.fu-berlin.de
Abstract: This paper describes the quantification of the extent to which phosphorus is incorporatedinto
polymer backbones during Suzuki polycondensation and gives details on how this step-growth
polymerization is best performed to ensure reproducibleresults specificallyregarding the achievable
molecular weights. © 1997 Published by ElsevierScienceLtd.
The Suzuki polycondensation has been developed into an important tool for the synthesis of
polyarylenes and related polymers.1 It is now one of the few established step-growth polymerizations which
proceed with formation of carbon-carbon bonds and, thus, complements the wealth of polyreactions which
lead to bond formation between carbon and hetero atoms. The great attraction of this polymerization originates
from its regiospecific course, its high functional group compatibility, and the high molecular weights which can
be achieved. It uses aryl boronic acids and aryl halides as coupling partners and Pd(0) complexes which
typically carry stabilizing phosphine ligands as catalyst precursors. The catalytic cycle is believed to involve
Pd(II) species, though an alternative suggestion has been made. 2 Recently, reports appeared in the literature
which shed light on potential side reactions of this cross-coupling. For example, Cheng reported on a facile
aryl-aryl exchange reaction between Pd center and phosphine ligands in Pd(II) complexes 3 and Marcuccio used
this exchange to explain that a certain boronic acid not only coupled with the aryl halide provided but also to
some extent with an aryl group of the phosphine ligand.4 Similar reactions have also been observed in the
related Stille cross-coupling. 5 In low molecular weight chemistry scrambling of aryl groups is disadvantagous
but may still be acceptable as long as the yields of side products are not too high and they can be separated off.
In Suzuki polycondensations, however, aryl-aryl scrambling would be devastating. It was Novak who pointed
out that phosphorus containing groups could not only by incorporated as terminator, but also as integral parts
of the backbone.6 He in fact found evidence for phosporous incorporation in a polycondensation. In the first
case, the rigid-rod character of the polyarylene backbone would be retained. In the second, however,
phosphorus acts as kink or even net-point. This would considerably decrease the value of this method for the
synthesis of structurally perfect rod-like polymers, which it was believed to be. We, therefore, decided to
investigate the issue of phosphorus incorporation in some depth and devised experiments (a) to see whether
the P-incorporation was a general phenomenon, (b) to quantify the degree of incorporation, and (e) to possibly
determine the way P is incorporated into the polymer structure. We also contribute to another matter of
importance in Suzuki polycondensationwhich is its reproducibility regarding the achievable molecular weights.
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