S 155 Bangladesh Journal of Medical Science, Vol : 20 Special Issue on Covid19, 2021 Original Article Neurological Manifestations of Covid-19 Hospitalized Patients In the state of Punjab, India Zahoor Ahmad Parry 1 , Swapnil Sunil Bumb 2 , Santosh Kumar 3 , Rohan Bhatt 4 , Mohammed Irfan 5 , Pragya Bhatt 6 . Abstract Introduction: COVID 19 often presents with fu-like symptoms. Elderly patients with systemic comorbidities are more likely to have severe COVID 19 infections and deaths. Severe neurological complications are frequently reported in severely and critically ill patients. In COVID-19, both central and peripheral nervous systems can be afected. The study aims to overview the spectrum, characteristics, and outcomes of neurologic manifestations associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods: A total of 1000 confrmed CoVID-19 patients were enrolled for the study. Demographic features and initial clinical manifestations were noted, and patients were followed during the hospital stay to develop any new neurological signs and symptoms. For analytical purposes, neurological presentations were grouped into the central nervous system, peripheral nervous system, and musculoskeletal system manifestations. Appropriate laboratory testing was employed as required on a case-to-case basis. Results: The mean age was 44.6 ± 14.3 years. 625 (62.5%) patients were male, while 375 (37.5%) were female. The neurological illness was a primary manifestation in 119 (11.9%) cases. These included encephalopathy (n=78), ischemic stroke (n=28), Guillain- Barre syndrome, (n=3), facial nerve palsy (n=4), and encephalitis (n=6). The most common neurological symptoms were headache 313 (31.3%) and hyposmia 52 (5.2%), followed by encephalopathy 78 (7.8%). More serious complications like seizures 18 (1.8%) and stroke 28 (2.8%) were also seen. Conclusion: CoVID-19 can present with a neurological illness, and we should remain vigilant to the possibility of neurological presentation of COVID-19 that can be thrombo-embolic, infammatory, or immune-mediated. Keywords: CNS, CoVID-19, Neurological, Pandemic, PNS, CoV-2 Correspondence: Dr Santosh Kumar, Department of Periodontology and Implantology, Karnavati University, Gandhinagar, Gujarat, India. Email: drsantoshkumar2004@gmail.com 1. Department of Neurology, Mogamedicity Superspeciality Hospital, Punjab, India Orcid ID: https://orcid.org/0000-0002-7157-9887. 2. Department of Public Health, ACPM Dental College, Dhule, Maharashtra, India Orcid ID: https://orcid.org/0000-0002-4009-0333 3. Professor, Department of Periodontology and Implantology, Karnavati University, Gandhinagar, Gujarat, India. Orcid ID: https://orcid.org/0000-0002-5117-7872 4. Department of Pedodontics, Karnavati University, Gandhinagar, Gujarat, India. Orcid ID: https://orcid.org/0000-0002-7962-3918 5. Department of Forensics, Federal University of Pelotas, Pelotas-RS, Brazil-96020-010, Orcid ID: https://orcid.org/0000-0003-0683-106X 6. Department of Human Anatomy, College of Physiotherapy, Janardhan Rai Nagar Vidyapeeth University, Udaipur, Rajasthan. Orcid ID: https://orcid.org/0000-0002-3928-8801. Bangladesh Journal of Medical Science, Special Issue on COVID-19. 2021. Page : 155-161 DOI: https://doi.org/10.3329/bjms.v20i5.55414 Introduction Coronavirus disease 2019 (COVID-19), linked to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is a widely spread infectious disease, with the frst cases reported in China in December 2019. 1,2 The virus has continued to spread since then. On Mar 11, 2020, the World Health Organization characterized COVID-19 as a pandemic. Common disease manifestations include respiratory tract and associated systemic manifestations, but neurologic manifestations, including headaches, dizziness, anosmia, encephalopathy, and stroke, have been reported in cohort studies. 3–5 Uncommon