Case Series
Incidence of Gastrointestinal Neuroendocrine Tumor: Case Series,
Armed Forces Hospital Southern Region, Hospital-Based Tumor
Board Registry
Abdullah Mohammed Albishi ,
1
Ahmed Mostafa Mohamed Mostafa,
2
Hatim Mahgoub Ali,
3
Yahia Atiah Alhagawi,
1
Mohamed F. Bazeed,
4
Mahmoud R. A. Hussein,
5
Elshfeia Elhag Mohmed Ali Aloba,
3
and Ahmed Youssef Aboelyazid
6
1
Gastroenterology and Endoscopy Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Saudi Arabia
2
Clinical Oncology, Faculty of Medicine, Ain-Shams University, Egypt
3
Oncology Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Saudi Arabia
4
Radiology Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Saudi Arabia
5
Pathology Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Saudi Arabia
6
Preventive Medicine Department, Armed Forces Hospital Southern Region, Khamis Mushayt, Saudi Arabia
Correspondence should be addressed to Abdullah Mohammed Albishi; dr.abdullah6975@gmail.com
Received 9 April 2020; Revised 27 August 2020; Accepted 7 October 2020; Published 20 October 2020
Academic Editor: Peter F. Lenehan
Copyright © 2020 Abdullah Mohammed Albishi et al. This is an open access article distributed under the Creative Commons
Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
is properly cited.
Neuroendocrine tumors are aggressive and rare tumors which can occur almost everywhere in the body. The annual incidence of
neuroendocrine tumors is 2.5-5 per 100000. We report seven cases of gastrointestinal neuroendocrine tumors which were
diagnosed and treated at our hospital from the time period of 2016-2018 knowing that the total number of our hospital tumor
board cases registry during the same period was 444 cases.
1. Introduction
Generally, Neuroendocrine tumors (NETs) are rare
tumors comprising ~2% of all malignancies [1] with the
gastrointestinal tract and the lung as the most common
sites [2].
Neuroendocrine tumors (NETs) are a heterogeneous
group of epithelial neoplastic proliferations arising in many
body organs. Irrespective of their primary site and of their
grade of differentiation, neoplastic cells share features of
neural and endocrine differentiation: the “neuro” property
is based on the identification of dense core granules that are
similar to dense core granules (DCGs) present in serotoner-
gic neurons, which store monoamines, and the “endocrine”
property refers to the synthesis and secretion of these mono-
amines which is about two-thirds of NETs that arise in the
gastrointestinal tract and pancreas [1, 3].
2. Case Reports
This case series describes seven cases of gastrointestinal
NETs diagnosed and presented in the tumor board at our
hospital from the time period starting from 01/01/2016 till
31/12/2018 as shown in Table 1. Out of seven cases, four were
male and three were females. Four patients out of seven
present beyond 60 years of age. Appendix is the most
common site of NETs in our hospital.
2.1. 1st Case. A 60-year-old male presented with abdominal
pain and vomiting with constipation for 4 days; CT of the
abdomen showed an enhancing mass at the ileocecal area
including the appendix; he was diagnosed as having complete
intestinal obstruction and underwent right hemicolectomy;
histopathology report showed goblet cell carcinoid of the
Hindawi
Case Reports in Oncological Medicine
Volume 2020, Article ID 8819392, 7 pages
https://doi.org/10.1155/2020/8819392