Vol.:(0123456789) 1 3
World Journal of Urology
https://doi.org/10.1007/s00345-018-2231-9
ORIGINAL ARTICLE
Is mini‑percutaneous nephrolithotomy a safe alternative
to extracorporeal shockwave lithotripsy in pediatric age group
in borderline stones? a randomized prospective study
Ahmed Farouk
1
· Ahmed Tawfck
1
· Mohamed Shoeb
1
· Mahmoud A. Mahmoud
1
· Diaa Eldin Mostafa
1
·
Mohamed Hasan
1
· Hany M. Abdalla
1
Received: 22 August 2017 / Accepted: 7 February 2018
© Springer-Verlag GmbH Germany, part of Springer Nature 2018
Abstract
Purpose The extracorporeal shockwave lithotripsy (ESWL) remains the most common frst line of treatment for renal stones
in the pediatric population. The purpose of this study is to evaluate and compare the outcomes of the ESWL and mini-
percutaneous nephrolithotomy (mini-PCNL).
Patients and methods A total of 108 patients younger than 12 years of age with 1–2 cm single renal stone (pelvic or calyceal)
were randomized into two groups, each containing 54 patients. Patients in group A were subjected to mini-PCNL using 16.5
Fr percutaneous sheath while those in group B underwent ESWL using Dornier Compact Sigma.
Results The stone-free rate (SFR) after frst session was 88.9% (48 cases) and 55.6% (30 cases) for groups A and B, respec-
tively. The diference is highly statistically signifcant P = 0.006. Two patients (3.7%) in group A needed 2nd session of
PCNL, while 18 patients (33.3%)in group B needed a 2nd session, of theses 18 patients six patients needed a 3rd session
of ESWL. After the third session of ESWL and second look PCNL the stone-free rates were 92.59% (50 cases) and 88.89%
(48 cases) for groups A and B, respectively, (P = 0.639), which is statistically insignifcant. The mean hospital stay and
fuoroscopy exposure were signifcantly longer in the mini-PCNL group. The complication rate in groups A and group B
were (22.2%) and (14.8%), respectively, which is statistically insignifcant (P = 0.484).
Conclusions According to Clavien grade of complications mini-PCNL is a safe procedure, and after three session of ESWL,
mini-PCNL has a similar stone-free rate with a lower retreatment rate. However, the mini-PCNL has more radiation exposure,
and requires a longer hospital stay.
Keywords Mini-percutaneous nephrolithotomy · ESWL · Extracorporeal shock wave lithotrips · Pediatric renal stone ·
Endourology
Abbreviations
PCNL Percutaneous nephrolithotomy
ESWL Extracorporeal shockwave lithotripsy
YAG Neodymium-doped yttrium aluminium garnet
CIRF Clinically insignifcant residual fragments
KUB Kidneys, ureters and bladder
US Ultrasonography
SFR Stone-free rate
Introduction
The incidence of pediatric renal stones has increased at an
annual rate of about 6–10% and is currently 50 per 100,000
[1]. Such stones can be managed either by extracorporeal
shockwave lithotripsy (ESWL), retrograde intrarenal surgery
(RIRS), percutaneous nephrolithotomy (PCNL), or open,
laparoscopic and robotic surgery [2].
ESWL is the frst line of treatment for pediatric renal
stones because it carries the advantages of a shorter hospital
stay, rapid recovery, minimal morbidity, acceptable success
rates and generally has a high safety profle [3]. Addition-
ally, the anatomic characteristics of the infant body such
as the small size and increased peristalsis and fexibility of
the child’s ureter make ESWL the main and favored type of
treatment [4].
* Ahmed Tawfck
murmer_urology26@hotmail.com
1
Department of Urology, Ain Shams University Hospital,
Cairo, Egypt