International Surgery Journal | February 2023 | Vol 10 | Issue 2 Page 299 International Surgery Journal Ramírez JAT et al. Int Surg J. 2023 Feb;10(2):299-302 http://www.ijsurgery.com pISSN 2349-3305 | eISSN 2349-2902 Case Report Peritoneal carcinomatosis as a pathway of metastatic dissemination in a patient with gastroesophageal junction cancer: case report and review José Á. Tovar Ramírez 1 , R. Lucano Valdés Ramos 2 , Miguel Á. Nava Jiménez 3 , Obed H. Grajeda Chávez 1 , Luis Arturo Camarillo R. 4 , Mariano Tovar Ponce 5 , Emmanuel Gómez García 5 , Mauricio Martínez Hurtado 5 , Daniela Rodríguez Ramírez 1 , Ludwigvan A. Bustamante S. 1 * INTRODUCTION An important characteristic of esophageal and EGJC is that metastases identified in more than 50% of patients at time of diagnosis, while more than 30% will develop metastases during the course of the disease. this being one of main causes of death in these patients. 1,2 Most frequently described sites of metastases are in descending order: liver, distant lymph nodes, lung, bone, and brain. 3,5 There are limited studies reporting differences in metastatic spread based on the location of the primary tumor, for example, upper EC versus cancer of the lower esophagus or esophagus-gastric junction. 6,7 However, it has been described that peritoneal carcinomatosis is a slightly less frequent form of metastatic presentation when it comes to classic esophageal adenocarcinoma, however it is more common to find it when it comes to adenocarcinoma of the esophageal-gastric junction. 8-10 CASE REPORT In the present work we report the case of a 78-year-old male, his comorbidities are arterial hypertension under pharmacological treatment, glaucoma under management with trabatan and timolol, chronic low back pain under management with buprenorphine and celecoxib patches, gastroesophageal reflux disease in occasional PPI management. Initially, the patient was identified in the general medicine consultation and sent to the endoscopy service who, after performing an upper digestive endoscopy and taking biopsies, integrated the diagnosis of Barrett's esophagus with high-grade dysplasia and stenosis of the distal third of the esophagus. The study protocol was carried out during the pandemic, so the ABSTRACT The oesophageal adenocarcinoma is an increasing pathology in the last decade, predominantly in the western population. A characteristic of esophageal cancer (EC) and esophageal-gastric junction cancer (EGJC) is the high percent of metastatic disease at the time of diagnosis one of the main causes of death in these patients. The present case is about a 78-year-old man, diagnosed with Barrett's esophagus with high-grade dysplasia and stenosis of distal third of esophagus, during surgery we found peritoneal carcinomatosis with implants in gut and no resectably disease. Keywords: EC, Peritoneal carcinomatosis, Surgery, Surgical oncology 1 General Surgery Department, North Central Hospital, PEMEX. Mexico City, Mexico 2 General Surgery Department, Monterrey Regional Hospital, ISSSTE, Monterrey City, Mexico 3 Medicine Faculty of Guerrero University of Medicine, Acapulco City, Mexico 4 General Surgery Department, General Zone Hospital Number 33, IMSS, Monterrey City, Mexico 5 General Surgery Department, Minatitlan Regional Hospital PEMEX, Veracruz, Mexico Received: 17 December 2022 Accepted: 08 January 2023 *Correspondence: Dr. Ludwigvan A. Bustamante S., E-mail: Lbustamantes1994@gmail.com Copyright: © the author(s), publisher and licensee Medip Academy. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. DOI: https://dx.doi.org/10.18203/2349-2902.isj20230270