Accepted Manuscript Title: Codon usage variation of Zika virus: the potential roles of NS2B and NS4A in its global pandemic Authors: Dechun Lin, Liqiang Li, Tian Xie, Qingqing Yin, Nitin Saksena, Rangke Wu, Wanyu Li, Geyang Dai, Jinmin Ma, Xiaohong Zhou, Xiao-Guang Chen PII: S0168-1702(17)30597-X DOI: https://doi.org/10.1016/j.virusres.2018.01.014 Reference: VIRUS 97332 To appear in: Virus Research Received date: 4-8-2017 Revised date: 26-1-2018 Accepted date: 29-1-2018 Please cite this article as: Lin, Dechun, Li, Liqiang, Xie, Tian, Yin, Qingqing, Saksena, Nitin, Wu, Rangke, Li, Wanyu, Dai, Geyang, Ma, Jinmin, Zhou, Xiaohong, Chen, Xiao- Guang, Codon usage variation of Zika virus: the potential roles of NS2B and NS4A in its global pandemic.Virus Research https://doi.org/10.1016/j.virusres.2018.01.014 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.