International Journal of Ayurvedic Medicine, Vol 13 (4), 2022; 1078-1082 Published online in http://ijam.co.in ISSN No: 0976-5921 Case Report Key Words: Mutrashmari, Urolithiasis, Herbal formulation, Gokushura, Punarnava. Introduction According to Acharya Sushruta, body is based on three basic pillars i.e. "Tristhuna" - Dosha, Dhatu and Mala. Among those the malas are produced as result of Pachana Kriya (digestion and metabolism) of food and eliminated from the body through their respective channels. Mootra is one of the Drava Malas for which a specialized production and excretion system is present in our body and is called as “Mootravaha Strotas.” “Mootrashmari” is the one of the most common disorder of the Mootravaha Strotus. (1) Acharya Sushruta has mentioned it as ashtaumahagada and antakapratima. (2) Madhavkara also mentioned it as “Yamopama”which means-”The god of death”. Explanation regarding aetiopathogenesis, classification, clinical features, prognosis and treatment modalities are given in detail. In Ayurveda, many kalpas with Ashmaribhedaka properties have been mentioned. (3) Sushrutacharya said that in tarunavasta mootrashmari is oushadhasadya and in pravruddavasta chedana should be done. (4) Prevalence rate of urolithiasis varies according to geographical distribution, sex and age and more commonly seen in subjects residing in countries with dry and hot climate. Urolithiasis occurs more commonly between 3 rd and 5 th decades in both sex and rarely occurs after 5 th decade. The prevalence rate of urolithiasis is 45-48%. In India, 5 to 7 million people in hot belt suffer from urinary calculus. (5) Urolithisis is splitted as uro –urine, lithos-stone which means formation of calculi in the urinary system. The main theory for calculi formation is super saturation, insufficiency of calculi inhibitors such as mucopolysaccharides, vitamin A deficiency. Although, Regional conditions, food habits, heredity may have contributed in formation of calculi. Mootrashmari can be correlated with urinary calculus. A calculus is a concretion usually composed of inorganic materials formed in urinary system, due to imbalance between promoters and inhibitors of crystallization in urine. It presents with clinical features like renal pain, ureteric colic, dysuria, hematuria and presence of calculus. (6) The management of the urinary calculi varies depending upon size, position of calculus etc. Conservative management includes hydro treatment, Efficacy of Novel Herbal Formulation in Efficacy of Novel Herbal Formulation in Conservative Management of Mutrashmari (Urolithiasis) - A Case Report Shubham Biswas 1* , Devyani Dasar 2 , Kiran Khandare 3 , Anita Wanjari 4 1. PG Scholar, 2. Associate Professor, 3. Professor, Department of Shalyatantra, 4. Professor, Department of Rasashastra Bhaishjya Kalpana, Mahatma Gandhi Ayurved College, Hospital & Research Centre, Salod (H); Datta Meghe Institute of Medical Sciences, Sawangi (M), Wardha. India. Abstract Introduction: Mutrashmari is a result of extensive processes that include a series of reactions that lead to the production of any urinary stone, i.e., a result of an unbalance of calculi producers and regulators in the kidney. The urinary calculi need surgical intervention and that may include side effects and recurrence. Aims and Objective: This study is having aim to find out the efficacy of herbal formulation in mutrashmari (urinary Calculi) Case Presentation: The patient of 26 years having Udarashoola (pain in abdomen) with mutrakruchata since 2 months and Saraktamutrata (red color urine) since 15 days. Material and methods: Classical textbooks, articles, online journals were referred. The raw material was taken from Institute level. Observation and Results: Results were obtained by Subjective and Objective Criteria on basis of signs and symptoms of mutrashmari. Discussion: The herbal formulation (Gokshura, Kulathha,Punarnava panchanga, Pashanabhed leaves) a unique combination was selected. This combination has Shoolagna (analgesic), Ashmari nashaka, Mutravardhaka (diuretics). In the case report, an attempt was taken to investigate the combined effects of herbal formulation, dietary modifications, and dietary regimen with regard to removal of urinary stone and prevention from any further complication. Results: This study shows effective result of herbal formulation in 8 mm urinary calculi within 1 month with no recurrence till one year. 1078 * Corresponding Author: Shubham Biswas PG Scholar, Department of Shalyatantra, Mahatma Gandhi Ayurved College Hospital and Research Centre, Salod (H), Datta Meghe Institute of Medical Sciences, Wardha India. Email Id: sgbiswas55555@gmail.com