speakers shared their experiences from Egypt and the US. Dis- cussions focused on prenatal versus postnatal, early-onset versus late-onset, and hospital versus community acquired neonatal infections. Five topics represented high priorities for research in Egypt: 1) maternal vaginal colonisation patterns and maternal vaginal screening practices for common and emerging pathogens, 2) risk factors associated with hospital-acquired infections in delivery rooms and neonatal intensive care units, 3) antimicro- bial resistance among pathogens affecting newborns in intensive care units, 4) education and compliance with infection control measures among staff, and 5) presentation and risk factors for neonatal infections associated with home deliveries. Webinar conferences will be conducted with each team to mature their project. A second workshop will be organised to develop a grant proposal for each research project to be submitted to interna- tional funding agencies. Conclusion To address neonatal infections related mortality and morbidities, stakeholders involved in the care of the newborns in Egypt need to develop a prioritised future research agenda. A central taskforce need to facilitate the assembly of multicenter, multidisciplinary teams across the country to study these issues in collaboration with international expertise and funding resources. PO-0555 PREDICTIVE VALUE OF ADMISSION SURFACE SWABS IN EARLY-ONSET NEONATAL SEPSIS IN EXTREMELY LOW BIRTH WEIGHT (ELBW) INFANTS IN A NEONATAL INTENSIVE CARE UNIT (NICU) 1 M Mustapa, 1 J Egyepong, 2 AK Abdul-Rahman. 1 Neonatal Intensive Care, Luton and Dunstable University Hospital NHS Foundation Trust, Luton, UK; 2 Public Health Directorate, Luton Borough Council, Luton, UK 10.1136/archdischild-2014-307384.1197 Introduction Early Onset Neonatal Sepsis (EONS) is a major contributor to morbidity and mortality in ELBW infants. Admis- sion surface swab cultures (SSC) form part of admission surveil- lance cultures, however its place in the management of EONS is questionable. Objective To determine: • Sensitivity, specificity and positive predictive value of SSC. • If culture result would reflect on mean CRP value in first 72 hrs. • If maternal swabs and mode of delivery correlated with microbiological result in the baby. Method • Retrospective cohort study. • All inborn ELBW infants admitted into a Level 3 NICU from January 2010–December 2013. • Maternal swabs; mode of delivery; infants SSC, blood cultures and mean CRP (within 72 h) were reviewed. Result • 161 ELBW infants were admitted and all had admission SSC, CRPs and blood cultures. • 25 of 161 (15.5%) had positive SSC (Figure 1) of which 5 were mixed culture results. • 11 of 161 (6.8%) had EONS (positive blood cultures) (Table 1). • 4 of 25 (16%) of positive SSC had correlating blood culture – all of which were E coli; 1 subject had positive SSC and blood culture but did not correlate. Abstract PO-0555 Figure 1 Bacteria grown from skinj swab Abstract PO-0555 Table 1 Bacteria grown from initial blood cultures Microorganism n (%) E coli 4 (36.3) S aureus 1 (9.1) Gram positive cocci 1 (9.1) Group B streptococcus 1 (9.1) Peptostreptococcus asaccharolyticus 1 (9.1) Coagulase negative staphyloccus 3 (27.2) Abstract PO-0555 Figure 2 Percentage of positive microbiological result for different mode of delivery Abstract PO-0555 Table 2 Mean CRP for different microbiological result Microbiological result Mean CRP Skin negative;Blood negative 5.8 Skin negative;Blood positive 9.3 Skin positive;Blood negative 17.2 Skin positive;Blood positive 15.0 F(3,10.164)=2.026, p = 0.173 Poster abstracts A432 Arch Dis Child 2014;99(Suppl 2):A1–A620 on May 27, 2020 by guest. Protected by copyright. http://adc.bmj.com/ Arch Dis Child: first published as 10.1136/archdischild-2014-307384.1197 on 14 October 2014. Downloaded from