_____________________________________________________________________________________________________ *Corresponding author: E-mail: Wanjari605@gmail.com; Journal of Pharmaceutical Research International 33(41B): 37-40, 2021; Article no.JPRI.71740 ISSN: 2456-9119 (Past name: British Journal of Pharmaceutical Research, Past ISSN: 2231-2919, NLM ID: 101631759) Caseating Tuberculous Lymphadenitis- A Case Report Mayur B. Wanjari 1* , Deeplata Mendhe 1 , Pratibha Wankhede 1 and Sagar Alwadkar 1 1 Department of Community Health Nursing, Smt. Radhikabai Meghe Memorial College of Nursing, Datta Meghe Institute of Medical Sciences, Sawangi (M), Wardha, Maharashtra, India. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JPRI/2021/v33i41B32342 Editor(s): (1) Dr. Sawadogo Wamtinga Richard, Ministry of Higher Education, Scientific Research and Innovation, Burkina Faso. Reviewers: (1) Takahiro Kitamura, Yao Municipal Hospital, Japan. (2) Issing, Peter Rolf, University of Gießen, Germany. Complete Peer review History: https://www.sdiarticle4.com/review-history/71740 Received 20 June 2021 Accepted 26 July 2021 Published 20 August 2021 ABSTRACT Introduction: Tuberculosis lymphadenitis (or tuberculous adenitis) is the most common type of infection with tuberculosis that occurs outside of the respiratory system. Tuberculosis lymphadenitis is a chronic condition caused by Mycobacterium tuberculosis in the granulomatous inflammation of the lymph node caused by caseated necrosis. The number of people who contact tuberculosis is estimated at 8 million per year, and about 3 million people die from tuberculosis in the world. Presentation of Case: In this case report we delineate the case of a female patient, 26-year-old, she had some pain and lymph node swelling in her right submandibular region since from 4 months and was diagnosed as right Caseating Tuberculous Lymphadenitis, associated with the cervical (neck) region, who was immunocompetent and HIV test negative, with a history of recurring fever, weight loss, loss of appetite for the last 4 months. On physical examination, she had swelling approximately 3×3 cm in the right submandibular region and a hard mass and painful sensation were noticed in her right submandibular region. On Fine needle aspiration cytology of submandibular lymph node reveals Caseating Tuberculous Lymphadenitis. this is extremely rare in immunocompetent individuals. Case Study