ACCEPTED MANUSCRIPT ACCEPTED MANUSCRIPT Title: Elevated Unmethylated and Methylated Insulin DNA are Unique Markers of A++ Ketosis Prone Diabetes Authors: Surya N Mulukutla a , Sarah A Tersey b , Christiane S Hampe c , Raghavendra G Mirmira b *, Ashok Balasubramanyam a * a Department of Medicine, Section of Diabetes and Endocrinology, Baylor College of Medicine, Houston, Texas, USA b Center for Diabetes and Metabolic Diseases, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, USA c Department of Medicine, University of Washington, Seattle, Washington, USA *Joint corresponding authors Corresponding Authors: Ashok Balasubramanyam, MD Diabetes Research Center, Division of Diabetes, Endocrinology and Metabolism Baylor College of Medicine, BCM R607, One Baylor Plaza, Houston, Texas, USA 77030 Telephone #: 713-798-8654; Fax #: 713-798-4585; E-mail: ashokb@bcm.edu Raghavendra G Mirmira, MD, PhD Center for Diabetes and Metabolic Diseases, Indiana University 635 Barnhill Drive, MS2031A, Indianapolis, IN, USA 46202 Telephone #: 317-274-4145; Fax #: 317-274-4107; Email: rmirmira@iu.edu Disclosures SNM, CSH and AB have no conflicts of interest. SAT and RGM have filed patent applications for assays to measure beta cell dysfunction and death. ___________________________________________________________________ This is the author's manuscript of the article published in final edited form as: Mulukutla, S. N., Tersey, S. A., Hampe, C. S., Mirmira, R. G., & Balasubramanyam, A. (2017). Elevated Unmethylated and Methylated Insulin DNA are Unique Markers of A + β + Ketosis Prone Diabetes. Journal of Diabetes and Its Complications. https://doi.org/10.1016/j.jdiacomp.2017.10.013