Suren Kumar Das et al JMSCR Volume 06 Issue 12 December 2018 Page 1162 JMSCR Vol||06||Issue||12||Page 1162-1168||December 2018 Resistance to Commonly Used Antimicrobial Agents in Bacterial Pathogens Isolated from Urinary Tract Infections in tertiary care teaching hospital Authors Suren Kumar Das 1 , Swayam Prabha Sahoo 2 , Debabrata Kumar Sabat 1 1 Department of Urology, IMS and SUM Hospital, Siksha O Anusandhan University, K 8, Kalinga Nagar, Bhubaneswar-751003, Odisha, India 2 Medical Research Laboratory, IMS and SUM Hospital, Siksha O Anusandhan University, K 8, Kalinga Nagar, Bhubaneswar-751003, Odisha, India *Corresponding Author Dr Debabrata Kumar Sabat Associate Professor, Dept of Urology, IMS and SUM Hospital, Bhubaneswar, 751003, Odisha, India Email: debabrat78@gmail.com Abstract The point of this examination was to get information on powerlessness examples of pathogens in charge of both network and healing center urinary tract contaminations (UTIs); and broke down hazard factors for disease caused by ciprofloxacin-safe Escherichia coli and expanded range β-lactamace (ESBL)- creating strains in Bhubaneswar, Odisha. Of 1,012 pee societies tentatively examined, a sum of 196 (19.3%) yielded noteworthy development of a solitary life form. The most well-known segregate (60.7%) was Escherichia coli . The anti-infection agents regularly utilized in UTIs are less compelling with the exception of Fosfomycin-trometamol and imipinem. The utilization of ciprofloxacin in the past a half year (chances proportion [OR] = 7.59 [1.75– 32.74]), utilization of different anti-toxins in the past a half year (OR = 1.02 [1.02– 2.34]), and creation of ESBL (OR = 19.32 [2.62– 142.16]) were observed to be related with ciprofloxacin obstruction among the E. coli disengages. Hazard factors for ESBL inspiration were the utilization of ciprofloxacin and third-age cephalosporin in the former a half year (OR = 3.05 [1.42– 6.58] or potentially = 9.78 [2.71– 35.25], individually); and being an inpatient (OR = 2.27 [1.79– 2.89]). Fosfomycin-trometamol could be incorporated as a sensible option for the treatment of uncomplicated UTI in Bhubaneswar, Odisha. Introductions Urinary tract disease (UTI) is a standout amongst the most vital reasons for horribleness in the all inclusive community, and is the second most normal reason for clinic visits (1) . With propelling age, the rate of UTI increments in men because of prostate amplification and neurogenic bladder (2) . Repetitive diseases are normal and can prompt irreversible harm of the kidneys, bringing about renal hypertension and renal disappointment in serious cases (3) . In the network, ladies are progressively inclined to create UTI. About 20% of ladies encounter a solitary scene of UTI amid their lifetime, and 3% of ladies have more than one scene of UTI per year (4) . Pregnancy likewise makes them progressively powerless to www.jmscr.igmpublication.org Impact Factor (SJIF): 6.379 Index Copernicus Value: 79.54 ISSN (e)-2347-176x ISSN (p) 2455-0450 DOI: https://dx.doi.org/10.18535/jmscr/v6i12.189