Confidential: For Review Only Overlapping cortical malformations in patients with pathogenic variants in GRIN1 and GRIN2B Journal: Journal of Medical Genetics Manuscript ID jmedgenet-2021-107971.R1 Article Type: Original research Date Submitted by the Author: 20-Nov-2021 Complete List of Authors: Brock, Stefanie; Universitair Ziekenhuis Brussel, Department of Pathology; Vrije Universiteit Brussel, Neurogenetics Research Group, Reproduction Genetics and Regenerative Medicine Research Cluster Laquerriere, Annie; INSERM U1245, Normandy Centre for Genomic and Personalized Medicine; Rouen University Hospital, Department of Pathology Marguet, Florent; INSERM U1245, Normandy Centre for Genomic and Personalized Medicine; Rouen University Hospital, Department of Pathology Myers, Scott J.; Emory University School of Medicine Atlanta, Department of Pharmacology and Chemical Biology; Emory University School of Medicine Atlanta, Center for Functional Evaluation of Rare Variants (CFERV), Hongjie, Yuan; Emory University School of Medicine, Department of Pharmacology and Chemical Biology; Emory University, Center for Functional Evaluation of Rare Variants (CFERV) Baralle, Diana; University of Southampton, Human Development and Health Vanderhasselt, Tim; Universitair Ziekenhuis Brussel (UZ Brussel), Department of Radiology Stouffs, Katrien; Universitair Ziekenhuis Brussel (UZ Brussel), Center for Reproduction and Genetics; Vrije Universiteit Brussel, Neurogenetics Research Group, Reproduction Genetics and Regenerative Medicine Research Cluster Keymolen, Kathelijn; Universitair Ziekenhuis Brussel, Center for Reproduction and Genetics Kim, Sukhan; Emory University School of Medicine Atlanta, Department of Pharmacology and Chemical Biology; Emory University School of Medicine Atlanta, Center for Functional Evaluation of Rare Variants (CFERV) Allen, James; Emory University School of Medicine Atlanta, Department of Pharmacology and Chemical Biology; Emory University School of Medicine Atlanta, Center for Functional Evaluation of Rare Variants (CFERV) Shaulsky, Gil; Emory University School of Medicine Atlanta, Department of Pharmacology and Chemical Biology; Emory University School of Medicine Atlanta, Center for Functional Evaluation of Rare Variants (CFERV) Chelly, Jamel; Université de Strasbourg, Institut de Génétique et de https://mc.manuscriptcentral.com/jmedgenet Journal of Medical Genetics