transient infections. We aimed to identify the population of adolescents infected with HPV and risk factors associated. Methods A cross-sectional study evaluating adolescents (from 10 to 19 years of age) carried out from January to August 2012 at the major Sexually Transmitted Infections (STI) Refer- ence Centre in Bahia, Brazil. Sociodemographic and clinical data were obtained by reviewing charts and analysed through SPSS 20.0. Results Of the adolescents evaluated, 324 had the diagnosis of HPV, evidencing an HPV prevalence of 62.5%. Among those, the mean age was 16.8 (±1.5) years and the sexual debut occurred at 13.2 (±3.5) years of age. There was an associa- tion between the female gender and the diagnosis of HPV (p<0.01; OR 3.22, 95% CI 2.18–4.77), as well as to being 16 years old or older (p<0.01; OR 3.44, 95% CI 2.28–5.19). Regarding lifestyle, 25.6% (42/164) of HPV patients reported alcohol use, 8.1% (16/197) illicit drugs use and 2.2% (3/138) were smokers. There was a statistical correlation between having 8 years of schooling and HPV (p=0.02; OR 1.76, 95% CI 1.10–2.79), as well as working and the infection (p=0.01; OR 2.54, 95% CI 1.17–5.53). As for clinical charac- teristics, 15.8% (40/253) of HPV patients were pregnant dur- ing the study, with a significant association between pregnancy and the virus (p=0.02; OR 2.69, 95% CI 1.10–6.58). There was 91.9% (295/321) of clinical diagnosis of HPV, and 61.9% (199/321) of genital warts among the infected population. 90.9% (280/308) of the infected adolescents underwent treat- ment for HPV. Conclusion The clinical and epidemiological profile of these adolescents revealed the need for prevention campaigns against STIs with accessible language, promoting access to informa- tion. Access to HPV vaccine is now possible, and it is still necessary to stimulate follow-up and treatment in order to reduce this infection and its associated diseases. P3.186 NEISSERIA GONORRHOEAE ANTIMICROBIAL RESISTANCE SURVEILLANCE IN JOHANNESBURG, SOUTH AFRICA 1 Ranmini Kularatne, 2 Venessa Maseko, 2 Lindy Gumede, 2 Frans Radebe, 1 Tendesayi Kufa- Chakezha. 1 National Institute for Communicable Diseases and University of The Witwatersrand, Johannesburg, South African Republic; 2 National Institute for Communicable Diseases, Johannesburg, South African Republic 10.1136/sextrans-2017-053264.421 Introduction Gonorrhoea is the predominant cause of sympto- matic male urethritis in South Africa. Neisseria gonorrhoeae has displayed an alarming propensity to acquire resistance to all sequential first-line antimicrobial agents used over the years. The National Institute for Communicable Diseases has co-ordinated STI microbiological surveillance since 2005 in order to validate existing national syndromic management guidelines. We describe Neisseria gonorrhoeae antimicrobial resistance patterns and trends from Johannesburg surveillance, spanning a period of eight years from 2008 to 2015. Methods Neisseria gonorrhoeae was cultured from swab speci- mens of genital discharge (endocervical and endourethral) from consenting adult patients presenting to a community- based primary healthcare facility in Johannesburg. The mini- mum inhibitory concentrations (MICs) of antimcrobials were determined using Etest (cefixime, ceftriaxone, ciprofloxacin) or agar dilution (azithromycin, penicillin, tetracycline). Clinical Laboratory Standards Institute (CLSI) criteria, where applicable, were used for interpretation of results. Descriptive statistics and likelihood-ratio tests in STATA 14 were used for data analysis. Results A total of 2,112 Neisseria gonorrhoeae isolates were tested for susceptibility to the extended-spectrum cephalospor- ins (ESCs) and ciprofloxacin. A proportion of these were tested for susceptibility to penicillin, tetracycline and azithro- mycin. Between 2011 and 2015, the prevalence of high-level resistance increased from 31% to 57% for penicillin (p=0.009) and 73% to 91% for tetracycline (p=0.009). Between 2008 and 2015, the prevalence of high-level cipro- floxacin resistance rose exponentially from 24% to 67% (p<0.001). Decreased susceptibility (DS) to cefixime was not observed; however one isolate from 2013 exhibited DS to cef- triaxone. Trend analysis revealed MIC creep for cefixime. Ele- vated azithromycin MICs of >0.5 mg/ml were identified only in 2015 (5/125; 4%). Conclusion Neisseria gonorrhoeae resistance trends for Johan- nesburg reveal that high-prevalence resistance to penicillin, tet- racycline and ciprofloxacin obviates their use for STI syndromic management. The prevalence of resistance to ESCs is <1% and to azithromycin <5%, validating their continued use in dual therapy. However, it is essential that ESC and azi- thromycin susceptibility trends are monitored to detect emerg- ing resistance timeously. P3.187 HIV AND STI PREVENTION AMONG YOUNG MEN WHO HAVE SEX WITH MEN (MSM) IN THE WESTERN REGION OF PUERTO RICO 1 Raquel Corchado, 2 Vivian Colon, 3 Edna Acosta, 4 Jorge Rodríguez, 5 Yara Sánchez, 5 Nelson Castillo, 6 Luis Nieves, 7 Jose Mulinelli, 8 Peter Shepard, 7 Cesar Concepcion. 1 Department of Social Sciences, Graduate School of Public Health, Medical Sciences Campus, Universit, San Juan – Puerto Rico; 2 Population Sciences Division, Puerto Rico Comprehensive Cancer Centre, San Juan – Puerto Rico; 3 Community Services Division, Centre for Evaluation and Sociomedical Research, Graduate School of Publ, San Juan – Puerto Rico; 4 Department of Health Services Administration, Graduate School of Public Health, Medical Sciences CA, San Juan – Puerto Rico; 5 Department of Biostatistics And Epidemiology, Graduate School of Public Health, Medical Sciences CA, San Juan – Puerto Rico; 6 Department of Social Sciences, Mayagüez Campus, University of Puerto Rico, Mayagüez – Puerto Rico; 7 Coaí INC, Mayagüez – Puerto Rico; 8. Coaí, INC, Mayagüez – Puerto Rico 10.1136/sextrans-2017-053264.422 Introduction According to the HIV Surveillance System, there has been an increase in newly reported cases of HIV among young men who have sex with men (YMSM) in Puerto Rico when compared to intravenous drug users. The Youth Preven- tion Program (YPREV) which aims to monitor high-risk practi- ces in young men (18–24 years old) and provide services for this population in the Western region of the island was devel- oped between the academia and community-based organisa- tions (CBOs) with the aim of decreasing health disparities in youth in universities and surrounding communities. This study presents data on the first year of the needs assessment con- cerning HIV testing and prevention methods as well as our ongoing efforts after gathering this data. Methods To determine the needs and outline the strategic plan of YPREV, a mixed methods approach was used. The first phase consisted of developing and carrying out a needs assessment which was performed from March 2016 until Sep- tember 2016. A total of 183 YMSM were recruited using a Abstracts A162 Sex Transm Infect 2017;93(Suppl 2):A1–A272 on June 8, 2020 by guest. Protected by copyright. http://sti.bmj.com/ Sex Transm Infect: first published as 10.1136/sextrans-2017-053264.421 on 8 July 2017. Downloaded from