A98 SLEEP, Volume 40, Abstract Supplement, 2017 A. Basic Sleep Science VI. Learning, Memory, Cognition deadly force. It is critical to assess officer performance in deadly force simulations to gain a better understanding of the effects of fatigue on deadly force judgement and decision making. The purpose of this study was to assess the effects of fatigue and shift work on a series of performance measures in simulated deadly force scenarios. Methods: Participants were experienced patrol officers recruited from a medium-sized law enforcement agency in the Inland Northwest (N=80). Subjects participated in two to four separate sessions in the lab, at least one directly following the last patrol shift of the work week (fatigued condition) and at least one at the same time of day after a three day rest period (control condition). Each five hour session included six deadly force scenarios and variety of cognitive tasks as well as multiple driving simulations. Results: Mixed effects analysis of variance found fatigued officers to outperform rested officers F (1, 1124) = 6.53, p = 0.01. Follow up Pearson chi-square analysis and nonlinear mixed effect regression analysis showed fatigued officers to perform significantly better on several distinct measures of performance. These performance items were primarily associated with measures of the officers’ immersion and engagement within the simulated deadly force scenario. Conclusion: Fatigue appears to lower the suspension of disbelief bar- rier seen within simulation-based training. This would explain why our fatigued law enforcement officers outperformed rested officers on the measures of performance which are associated with immersion and engagement with the simulated scenario. A more complete understand- ing of the physiological differences of these officers within the simulation would provide a clearer picture of participant engagement and immersion. Support (If Any): 0267 SLEEP DISORDERED BREATHING AND LOW SCHOOL PERFORMANCE Harding R, Schaughency E, Haszard J, Galland B University of Otago, Dunedin, NEW ZEALAND Introduction: The SEALION (Sleep Education and Learning in Our Neighbourhood) study aimed to estimate the prevalence of sleep-dis- ordered breathing (SDB) in a large community sample of New Zealand (NZ) 6 to 10-year-old children and investigate whether children with SDB are more at risk for not progressing adequately within the NZ curriculum. Methods: Parents/caregivers of 6 to 10 year-old children were recruited through NZ primary schools and parent-targeted Facebook advertisements. 1621 NZ parents/caregivers completed the on-line survey covering items including: the extent and severity of SDB symp- toms (SDB scale of the Pediatric Sleep Questionnaire); and children’s academic performance based on teacher feedback relative to National Standards (well below/below/at/above) across domains of reading, writing, and mathematics. Results: Preliminary analysis (n=1621) shows the prevalence of children “at risk” of SDB as rated by their parents was 19.0% (95% CI = 17.1 - 21.0%). The proportion of children “at risk” of SDB who were achieving below the National Standards was 26.3% for reading, 32.8% for writing, and 29.2% for maths. Of the children “not at risk” of SDB, 13.5% were achieving below National Standards for reading, 18.6% for writing, and 13.5% for math, according to parent report. For those children at risk of SDB, the odds ratio of being below the National Standards compared to those not at risk was 1.9 for reading, 1.8 for writing, and 2.2 for math, after adjustment for ethnicity, gender, age, and mother’s education (all P < 0.01). Conclusion: These preliminary findings suggest that more NZ children with, than without, SDB may be performing below National Standards for academic performance. Equipping teachers and parents to be able to identify children at risk of sleep problems could facilitate early screen- ing and referral for possible diagnosis and treatment to benefit the chil- dren’s long term health and potentially academic development. Support (If Any): Freemasons of New Zealand Fellowship in Paediatrics, The Grand Lodge of New Zealand. 0268 ROLE OF INTERMITTENT HYPOXIA AND SLEEP FRADMENTATION FROM OSA DURING SLOW WAVE SLEEP ON SPATIAL MEMORY Kam K 1 , Castillo B 1 , Chua N 1 , Sanders H 1 , Rapoport DM 1 , Ayappa I 1 , Osorio RS 2 , Varga AW 1 1 Icahn School of Medicine at Mount Sinai, New York, NY, 2 NYU School of Medicine, New York, NY Introduction: Slow wave sleep (SWS) is thought to benefit spatial memory consolidation. This study investigates whether disrupting SWS via sleep-stage specific OSA affects spatial memory consolida- tion and how sleep fragmentation and intermittent hypoxia differen- tially impact this effect. Methods: We recruited 5 subjects with severe OSA who are well treated and compliant with CPAP. Individual subjects spent 3 different nights in the lab and performed timed trials before and after sleep on unique but equally difficult 3D spatial mazes. The 3 conditions included: 1) consolidated sleep with treated OSA 2) CPAP withdrawn exclusively in SWS (SWS-OSA) and 3) CPAP withdrawn exclusively in SWS with simultaneous addition of supplemental oxygen (SWS-OSA+O2). Results: CPAP withdrawal in SWS both decreased %SWS (21% +/- 11% during consolidated sleep vs. 13% +/- 7% with SWS-OSA), and fragmented remaining SWS (SWS apnea hypopnea index with 3% oxygen desaturation or arousal (AHI3A) = 0.5/hour +/- 1 during consolidated sleep vs. 36/hour +/- 12 with SWS-OSA). During SWS- OSA+O2, SWS was also reduced (11% +/ 8%) and respiratory events continued (AHI3A 31/hour +/- 20), however indices of oxygen desat- uration were minimized (%time below 90% in SWS = 4.3% +/- 1.7% during SWS-OSA vs 0.5% +/- 0.9% during SWS-OSA+O2; average oxygen saturation during respiratory event = 88.7% +/- 3.3% during SWS-OSA vs. 94% +/- 1.4% during SWS-OSA+O2). During consoli- dated sleep, median completion time improved from 180 sec pre-sleep (range 86 to 248 sec) to 111 sec post-sleep (range 87 to 412 sec) (38%). During SWS-OSA median completion time improved from 138 sec pre-sleep (range 116 to 272 sec) to 133 sec post-sleep (range 73 to 453 sec) (4%) and during SWS-OSA+O2 median completion time improved from 172 sec pre-sleep (range 61 to 339 sec) to 161 sec post- sleep (range 51 to 306 sec) (6%). Conclusion: CPAP withdrawal during SWS in subjects with severe OSA reduces and fragments SWS. The addition of supplemental oxy- gen during CPAP withdrawal minimizes the associated intermittent hypoxia. Early evidence suggests a greater benefit of consolidated sleep on overnight change in spatial navigation performance than sleep with SWS disruption either with or without intermittent hypoxia. Support (If Any): 0269 INSOMNIA, SHORT SLEEP DURATION, AND FAILED TEST PERFORMANCE IN A MILITARY ACADEMIC SETTING McDonald JL 1 , Lopez AA 1 , Lee JD 1 , Capaldi VF 2 , LoPresti ML 1 1 US Army Medical Research Directorate West, Tacoma, WA, 2 Walter Reed Army Institute of Research, Silver Spring, MD Introduction: College age students often obtain poor sleep and expe- rience adverse physical and mental health outcomes as a result, which Downloaded from https://academic.oup.com/sleep/article/40/suppl_1/A98/3781492 by guest on 21 June 2023